Evidence map›Paper›PMID 23714309›Full record

ReviewHematology/oncology clinics of North America2013

Immune thrombocytopenia.

Gaurav Kistangari, Keith R McCrae

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Hematology/oncology clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 86 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04482777 unknown statusnot on this mapstarted 2023, after this paper: background citation

IL37,Tlymphocytes ,NK Cells in Pathogenesis of Immune Thrombocytopenia.

TypeobservationalSponsorAssiut UniversityRan2023 to 2023Enrolled90ConditionsITPArmsCorticosteriod for treated patients
NCT05455983 unknown statusnot on this mapstarted 2022, after this paper: background citation

Relationship Between Different Types of COVID-19 Vaccine and Development of Immune Thrombocytopenic Purpura

TypeobservationalSponsorAssiut UniversityRan2022 to 2023Enrolled500ConditionsCOVID-19 VaccineArmscovid19 vaccines
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Evaluation ofFrontiers in medicine · 2026
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
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  13. Article
  14. Review
  15. Article
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  18. Article
  19. Avatrombopag for the Treatment of Immune Thrombocytopenia.European journal of haematology · 2025
    Review
  20. Review

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gaurav KistangariDepartment of Hospital Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.
Keith R McCrae

Funding

Regulation of Angiogenesis by KininogenR01HL089796 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MCCRAE, KEITH R. · 2009 to 2013
$2.0M
Transfusion Medicine/Hemostasis Clinical Research NetworkU01HL072033 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MCCRAE, KEITH R. · 2002 to 2012
$1.7M
NHLBI NIH HHS R01 HL089796NHLBI NIH HHS U01 HL072033
6 · The paper itself

Abstract

Immune thrombocytopenia (ITP) is a common hematologic disorder characterized by isolated thrombocytopenia. ITP presents as a primary or a secondary form. ITP may affect individuals of all ages, with peaks during childhood and in the elderly, in whom the age-specific incidence of ITP is greatest. Bleeding is the most common clinical manifestation of ITP. The pathogenesis of ITP is complex, involving alterations in humoral and cellular immunity. Corticosteroids remain the most common first line therapy for ITP. This article summarizes the classification and diagnosis of primary and secondary ITP, as well as the pathogenesis and options for treatment.

Indexed as

Purpura, Thrombocytopenic, IdiopathicHumans

Identifiers

PMID23714309
PMCPMC3672858

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.