Evidence map›Paper›PMID 23714307›Full record

ReviewHematology/oncology clinics of North America2013

Genetic dissection of platelet function in health and disease using systems biology.

Wadie F Bahou

Open access · greenAbstract readReview
In one paragraph

Review in Hematology/oncology clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Wadie F BahouDepartment of Medicine, Health Sciences Center, Stony Brook University, Stony Brook, NY 11794-8151, USA. wadie.bahou@sbumed.org
Stony Brook University · US

Funding

World Trade Center Worker and Volunteer Medical Screening ProgramM01RR010710 · NCRR · STATE UNIVERSITY NEW YORK STONY BROOK · PI GOLDSTEIN, RITA Z · 1998 to 2009
$17.6M
Platelet Systems Biology in Health and DiseaseR01HL119096 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BAHOU, WADIE F · 2015 to 2019
$3.5M
Genetic dissection of the platelet thrombohemorrhagic phenotypeR01HL091939 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI BAHOU, WADIE F · 2009 to 2012
$1.6M
NCRR NIH HHS M01 RR010710NHLBI NIH HHS HL 091939NHLBI NIH HHS R01 HL091939NHLBI NIH HHS R01 HL119096
6 · The paper itself

Abstract

Technological advances in protein and genetic analysis have altered the means by which platelet disorders can be characterized and studied in health and disease. When integrated into a single analytical framework, these collective technologies are referred to as systems biology, a unified approach that links platelet function with genomic/proteomic studies to provide insight into the role of platelets in broad human disorders such as cardiovascular and cerebrovascular disease. This article reviews the historical progression of these applied technologies to analyze platelet function, and demonstrates how these approaches can be systematically developed to provide new insights into platelet biomarker discovery.

Indexed as

Systems BiologyBlood Platelet DisordersBlood PlateletsHumansPrognosis

Identifiers

PMID23714307
PMCPMC3767180
OpenAlexW2060340972

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.