Evidence map›Paper›PMID 23713595›Full record

ArticleCOPD2013

Impact of co-morbidities on self-rated health in self-reported COPD: an analysis of NHANES 2001-2008.

Nirupama Putcha, Milo A Puhan, Nadia N Hansel, M Brad Drummond, Cynthia M Boyd

Abstract read
In one paragraph

Article in COPD, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nirupama PutchaJohns Hopkins School of Medicine, Department of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland 21224, USA. nputcha1@jhmi.edu
Milo A Puhan
Nadia N Hansel
M Brad Drummond
Cynthia M Boyd

Funding

Institute for Clinical and Translational Research (UL1)UL1RR025005 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$75.8M
MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Sleep Related Mechanisms of COPD ProgressionP50HL084945 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI WISE, ROBERT A. · 2007 to 2011
$15.1M
Oxidative Stress & Inflammation in a Human PM Nasal ChallengeP50ES015903 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BREYSSE, PATRICK N · 2007 to 2011
$12.1M
Project 3: Dissecting the Diet Asthma Relationship in Mice Models of AsthmaP01ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI BISWAL, SHYAM · 2009 to 2013
$4.2M
Mechanisms of COPD Subphenotype DevelopmentK23HL103192 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DRUMMOND, MICHAEL BRADLEY · 2010 to 2013
$650k
Treatment Burden in Older Adults with Diabetes and MultimorbidityK23AG032910 · NIA · JOHNS HOPKINS UNIVERSITY · PI BOYD, CYNTHIA MELINDA · 2009 to 2013
$533k
Improving Clinical Practice Guidelines for Complex PatientsR21HS018597 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI BOYD, CYNTHIA MELINDA · 2009 to 2009
$236k
AHRQ HHS R21 HS018597AHRQ HHS R21 HS018597-01NCRR NIH HHS 5UL1RR025005-04NCRR NIH HHS UL1 RR025005NHLBI NIH HHS 1P50HL084945-01NHLBI NIH HHS K23 HL103192NHLBI NIH HHS K23HL103192NHLBI NIH HHS P50 HL084945NHLBI NIH HHS T32 HL007534NHLBI NIH HHS T32HL007534NIA NIH HHS K23 AG032910NIEHS NIH HHS 1P50ES015903-01NIEHS NIH HHS P01 ES018176NIEHS NIH HHS P50 ES015903
6 · The paper itself

Abstract

Chronic Obstructive Pulmonary Disease (COPD) coexists with co-morbidities. While co-morbidity has been associated with poorer health status, it is unclear which conditions have the greatest impact on self-rated health. We sought to determine which, and how much, specific co-morbid conditions impact on self-rated health in current and former smokers with self-reported COPD. Using the 2001-2008 National Health and Nutrition Examination Survey we characterized the association between thirteen co-morbidities and health status among individuals self-reporting COPD. Adjusted odds ratios (ORs) were generated using ordinal logistic regression. Additionally we evaluated the impact of increasing number of co-morbidities with self-rated health. Eight illnesses had significant associations with worse self-rated health, however after mutually adjusting for these conditions, congestive heart failure (OR 3.07, 95% CI 1.69-5.58), arthritis (OR 1.69, 95% CI 1.13-2.52), diabetes (OR 1.63, 95% CI 1.01-2.64), and incontinence/prostate disease (OR 1.63, 95% CI 1.01-2.62) remained independent predictors of self-rated health. Each increase in co-morbidities was associated with a 43% higher chance of worse self-rated health (95% CI 1.27-1.62). Individuals with COPD have a substantial burden of co-morbidity, which is associated with worse self-rated health. CHF, arthritis, diabetes and incontinence/prostate disease have the most impact on self-rated health. Targeting these co-morbidities in COPD may result in improved self-rated health.

Indexed as

Health StatusAgedArthritisComorbidityDiabetes MellitusFemaleHeart FailureHumansMaleMiddle AgedNutrition SurveysPrevalenceProstatic DiseasesPulmonary Disease, Chronic ObstructiveSelf ReportUrinary Incontinence

Identifiers

PMID23713595
PMCPMC4459792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.