ArticleScientific reports2013
Molecular epidemiology of community-associated methicillin-resistant Staphylococcus aureus in the genomic era: a cross-sectional study.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02363166 (Molecular Epidemiology and Phylodynamic and Phylogeographic Analysis of Community-associated Methicillin-resistant Staphylococcus Aureus), which is not on this map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Molecular Epidemiology and Phylodynamic and Phylogeographic Analysis of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA) Transmission: An Emergency Department Population Sampling Strategy
Who cites it
28 citing papers in PubMed.
- Fast hospital discharge rates blur within-hospital 'transmission footprint' in bacterial genomes, as showcased with Staphylococcus aureus.PLoS computational biology · 2026Article
- Dynamic Networks of Methicillin-ResistantOpen forum infectious diseases · 2025Article
- Antiretroviral Therapy Concealment Behaviors and their Association with Antiretroviral Therapy Adherence among People with HIV: Findings from the Florida Cohort Study.AIDS and behavior · 2024Article
- Prospective Genomic Surveillance Reveals Cryptic MRSA Outbreaks with Local to International Origins among NICU Patients.Journal of clinical microbiology · 2023Article
- TheFrontiers in microbiology · 2023Article
- Phylodynamic signatures in the emergence of community-associated MRSA.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The role of vaccines in combatting antimicrobial resistance.Nature reviews. Microbiology · 2021Review
- Estimated Methicillin-Resistant Staphylococcus aureus Decolonization in Intensive Care Units Associated With Single-Application Chlorhexidine Gluconate or Mupirocin.JAMA network open · 2021Article
- Increased Incidence and Plasma-Biofilm Formation Ability of SCCFrontiers in cellular and infection microbiology · 2021Article
- CA-MRSA and HA-MRSA coexist in community and hospital settings in Uganda.Antimicrobial resistance and infection control · 2019Article
- Whole-genome epidemiology, characterisation, and phylogenetic reconstruction of Staphylococcus aureus strains in a paediatric hospital.Genome medicine · 2018Article
- Article
- Distribution of the Most PrevalentFrontiers in microbiology · 2018Review
- Genomic Characterization of USA300 Methicillin-Resistant Staphylococcus aureus (MRSA) to Evaluate Intraclass Transmission and Recurrence of Skin and Soft Tissue Infection (SSTI) Among High-Risk Military Trainees.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Chromogenic media for MRSA diagnostics.Molecular biology reports · 2016Review
- The Impact of Selection, Gene Conversion, and Biased Sampling on the Assessment of Microbial Demography.Molecular biology and evolution · 2016Article
- Comparing the epidemiology of hospital-acquired methicillin-resistant Staphylococcus aureus clone groups in Alberta, Canada.Epidemiology and infection · 2016Article
- Role of Berberine in the Treatment of Methicillin-Resistant Staphylococcus aureus Infections.Scientific reports · 2016Article
- Identifying the effect of patient sharing on between-hospital genetic differentiation of methicillin-resistant Staphylococcus aureus.Genome medicine · 2016Article
- Genomic Epidemiology of Methicillin-Resistant Staphylococcus aureus in a Neonatal Intensive Care Unit.PloS one · 2016Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of healthcare-associated infections and significant contributor to healthcare cost. Community-associated-MRSA (CA-MRSA) strains have now invaded healthcare settings. A convenience sample of 97 clinical MRSA isolates was obtained from seven hospitals during a one-week period in 2010. We employed a framework integrating Staphylococcus protein A typing and full-genome next-generation sequencing. Single nucleotide polymorphisms were analyzed using phylodynamics. Twenty-six t002, 48 t008, and 23 other strains were identified. Phylodynamic analysis of 30 t008 strains showed ongoing exponential growth of the effective population size the basic reproductive number (R0) ranging from 1.24 to 1.34. No evidence of hospital clusters was identified. The lack of phylogeographic clustering suggests that community introduction is a major contributor to emergence of CA-MRSA strains within hospitals. Phylodynamic analysis provides a powerful framework to investigate MRSA transmission between the community and hospitals, an understanding of which is essential for control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.