Evidence map›Paper›PMID 23712477›Full record

ReviewWorld journal of microbiology & biotechnology2013

Gassericin A: a circular bacteriocin produced by lactic acid bacteria Lactobacillus gasseri.

Neha Pandey, R K Malik, J K Kaushik, Garima Singroha

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of microbiology & biotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 66 citations in OpenAlex.

  1. Review
  2. Bacteriocins fromFrontiers in microbiology · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Cell-free supernatant ofFrontiers in cellular and infection microbiology · 2024
    Article
  8. Review
  9. Review
  10. DoesCancers · 2022
    Review
  11. Article
  12. Strategies for Biocontrol ofFoods (Basel, Switzerland) · 2022
    Review
  13. A novel of new class II bacteriocin fromFrontiers in microbiology · 2022
    Article
  14. The microbiome-shaping roles of bacteriocins.Nature reviews. Microbiology · 2021
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. [Design, screening and antimicrobial activity of novel peptides againstNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2019
    Article
  20. Effect of Prebiotics-Enhanced Probiotics on the Growth ofInternational journal of microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Neha PandeyDairy Microbiology Division, National Dairy Research Institute, Karnal, 132001, India, neha.ambk@gmail.com.
R K Malik
J K Kaushik
Garima Singroha
National Dairy Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the recent years extensive efforts have been made to find out bacteriocins from lactic acid bacteria (LAB) active against various food spoilage and pathogenic bacteria, and superior stabilities against heat treatments and pH variations. Bacteriocins isolated from LAB have been grouped into four classes. Circular bacteriocins which were earlier grouped among the four groups of bacteriocins, have recently been proposed to be classified into a different class, making it class V bacteriocins. Circular bacteriocins are special molecules, whose precursors must be post translationally modified to join the N to C termini with a head-to-tail peptide bond. Cyclization appears to make them less susceptible to proteolytic cleavage, high temperature and pH, and, therefore, provides enhanced stability as compared to linear bacteriocins. The advantages of circularization are also reflected by the fact that a significant number of macrocyclic natural products have found pharmaceutical applications. Circular bacteriocins were unknown two decades ago, and even to date, only a few circular bacteriocins from a diverse group of Gram positive organisms have been reported. The first example of a circular bacteriocin was enterocin AS-48, produced by Enterococcus faecalis AS-48. Gassereccin A, produced by Lactobacillus gasseri LA39, Reutericin 6 produced by Lactobacillus reuteri LA6 and Circularin A, produced by Clostridium beijerinickii ATCC 25,752, are further examples of this group of antimicrobial peptides. In the present scenario, Gassericin A can be an important tool in the food preservation owing to its properties of high pH and temperature tolerance and the fact that it is produced by LAB L. gasseri, whose many strains are proven probiotic.

Indexed as

BacteriocinsAmino Acid SequenceAnti-Bacterial AgentsCyclizationFood PreservationGram-Negative BacteriaGram-Positive BacteriaLactic AcidLactobacillusProbioticsSequence HomologyAnti-Bacterial AgentsBacteriocinscircularin Aenterocin AS-48, Enterococcus faecalisgassericin ALactic Acid

Identifiers

PMID23712477
OpenAlexW2001542806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.