Evidence map›Paper›PMID 23712416›Full record

ArticleScientific reports2013

A novel protocol for three-dimensional structure prediction of RNA-protein complexes.

Yangyu Huang, Shiyong Liu, Dachuan Guo, Lin Li, Yi Xiao

Abstract read
In one paragraph

Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Methods and Applications in Proteins and RNAs.Life (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Review
  10. Computational tools to study RNA-protein complexes.Frontiers in molecular biosciences · 2022
    Review
  11. Article
  12. RNA and DNA G-quadruplexes bind to human dicer and inhibit its activity.Cellular and molecular life sciences : CMLS · 2021
    Article
  13. Article
  14. Methods and Applications of In Silico Aptamer Design and Modeling.International journal of molecular sciences · 2020
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yangyu HuangDepartment of Physics Huazhong University of Science and Technology, Wuhan 430074, Hubei, China.
Shiyong Liu
Dachuan Guo
Lin Li
Yi Xiao

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional structures of RNA-protein complexes are crucial for understanding their diverse functions. However, the number of the RNA-protein complex structures solved by experiments is still limited at present. To solve this problem, some computational protocols have been proposed to predict three-dimensional RNA-protein complex structures. But the prediction accuracies of these protocols are lower. The reason may be that these protocols don't fully incorporate the features of RNA-protein interfaces. Here we propose a novel computational protocol for three-dimensional RNA-protein complex structure prediction, 3dRPC, which applies new schemes to the discreteness of molecule and charge in docking algorithm and the construction of the reference state in scoring function in order to take account of the features of RNA-protein interfaces. This protocol achieves a high accuracy comparable to the well-developed algorithms for three-dimensional structure prediction of protein-protein complexes when tested on a RNA-protein docking benchmark.

Indexed as

AlgorithmsComputational BiologyModels, MolecularNucleic Acid ConformationProtein ConformationProteinsRNASoftwareProteinsRNA

Identifiers

PMID23712416
PMCPMC3664894

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.