ReviewNature reviews. Microbiology2013
The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium.
Review in Nature reviews. Microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 820 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
820 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effectiveness of oxidative therapies in mature oral biofilms: A systematic review and meta-analysis.Clinical oral investigations · 2026Pooled it
- Role of remote ischaemic conditioning in fracture healing and orthopaedic surgery-a systematic review and narrative synthesis.Journal of orthopaedic surgery and research · 2025Pooled it
- Phosphorylation of a novel STK substrate SstP1 links SUF Fe-S cluster biogenesis to oxidative stress resistance and virulence inVirulence · 2026Article
- High-throughput transposon sequencing identifies HprR as a key regulator of the LEE operon and virulence inVirulence · 2026Article
- ISEmerging microbes & infections · 2026Article
- A mathematical theory of redox biology.Royal Society open science · 2026Article
- Single-Cell Membrane-Permeabilization Kinetics Reveal Species-Specific Responses to Antimicrobial Photodynamic Treatment.ACS omega · 2026Article
- Reuterin alleviates Enterohemorrhagic Escherichia coli O157:H7-induced infectious diarrhea in mice through modulation of the gut microbiota.World journal of microbiology & biotechnology · 2026Article
- Synergistic Ionic Liquid-Antibiotic Combination as a Strategy against Methicillin-ResistantACS omega · 2026Article
- Antimicrobial Strategies in the Era of Resistance: It Is Too Early to Give Up Antibiotic Therapy.International journal of molecular sciences · 2026Review
- Selection favors cost-ordered adaptive mutational paths in a stress-magnitude-dependent manner.EMBO reports · 2026Article
- Conserved vulnerability of SoxR underlies zinc-mediated redox disruption and synergistic killing inmBio · 2026Article
- Description of Dorea chungnamensis sp. nov., an Aerotolerant Anaerobe Isolated from Pig Feces.Current microbiology · 2026Article
- Metal nanoparticles as next-generation therapeutics against antimicrobial resistance: mechanisms, functionalization, and translational potential.Molecular biology reports · 2026Review
- S267P mutation of OxyR regulator inSynthetic and systems biotechnology · 2026Article
- Genome-based predictions of metabolic preferences and substrate phenotypes in psychrotrophic bacteria from permafrost environments.Microbiology spectrum · 2026Article
- Exploratory Label-Free Proteomic Profiling of theMicroorganisms · 2026Article
- Mitochondria Meet the Lung Microbiome: A Bidirectional Dialogue in Inflammation and Respiratory Diseases.Biomedicines · 2026Review
- PET Micro(nano)plastics Modulate Metformin-Albumin Binding and Species-Specific Bacterial Responses.International journal of molecular sciences · 2026Article
- Transition Metal Activation Reframes SAMHD1 Regulation.ACS chemical biology · 2026Article
760 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Oxic environments are hazardous. Molecular oxygen adventitiously abstracts electrons from many redox enzymes, continuously forming intracellular superoxide and hydrogen peroxide. These species can destroy the activities of metalloenzymes and the integrity of DNA, forcing organisms to protect themselves with scavenging enzymes and repair systems. Nevertheless, elevated levels of oxidants quickly poison bacteria, and both microbial competitors and hostile eukaryotic hosts exploit this vulnerability by assaulting these bacteria with peroxides or superoxide-forming antibiotics. In response, bacteria activate elegant adaptive strategies. In this Review, I summarize our current knowledge of oxidative stress in Escherichia coli, the model organism for which our understanding of damage and defence is most well developed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.