Evidence map›Paper›PMID 23712257›Full record

ArticleChimerism

Reconsidering the bio-detection of tolerance in renal transplantation.

Faouzi Braza, Jean Paul Soulillou, Sophie Brouard

Abstract read
In one paragraph

Article in Chimerism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Faouzi BrazaInstitut National de la Santé et de la Recherche Médicale INSERM U643, Nantes, France. faouzi.braza@etu.univ-nantes.fr
Jean Paul Soulillou
Sophie Brouard

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Operational tolerance in kidney transplantation tolerance is rare phenomenon. It concerns recipients who keep a good function of their graft without immunosuppressors for more than one year. A critical need in the field of transplantation tolerance is the identification of biomarkers able to detect precociously tolerance phenotype in stable recipient in order to adapt treatment and progressively stop immunosuppressive therapy. But many limitations in these studies slow the application in clinics of such tolerance signature. In this addendum article we talk about these limitations and potential new directions to improve our approach in the quest of tolerance biomarkers.

Indexed as

Immunosuppression TherapyKidney TransplantationBiomarkersGene Expression ProfilingHumansTransplantation ToleranceBiomarkersDNA microarraykidneyoperational tolerancesignaturetransplantationTtolerance

Identifiers

PMID23712257
PMCPMC3654731

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.