Evidence map›Paper›PMID 23711982›Full record

ReviewMolecular psychiatry2013

Influence of the modern light environment on mood.

T A Bedrosian, R J Nelson

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02653040 (Light as an Aid for Recovery in Psychiatric Inpatients), which is not on this map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02653040 nacompletednot on this mapstarted 2015, after this paper: background citation

Light as an Aid for Recovery in Psychiatric Inpatients: A Pragmatic Randomized Controlled Pilot Trial

TypeinterventionalSponsorUniversity of AarhusRan2015 to 2018Enrolled54ConditionsMental IllnessArmsDynamic lighting
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Review
  6. Influence of Artificial Light at Night on Thyroid Gland Histology inAnimals : an open access journal from MDPI · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. The Effects of Light on Vertebrate Welfare: A Review.Animals : an open access journal from MDPI · 2025
    Review
  12. Review
  13. Oxytocin, Vasopressin and Stress: A Hormetic Perspective.Current issues in molecular biology · 2025
    Review
  14. Article
  15. Computational and structural biotechnology journal · 2025
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

T A BedrosianDepartment of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA. Bedrosian.2@osu.edu
R J Nelson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans and other organisms have adapted to a consistent and predictable 24-h solar cycle, but over the past ~130 years the widespread adoption of electric light has transformed our environment. Instead of aligning behavioral and physiological processes to the natural solar cycle, individuals respond to artificial light cycles created by social and work schedules. Urban light pollution, night shift work, transmeridian travel, televisions and computers have dramatically altered the timing of light used to entrain biological rhythms. In humans and other mammals, light is detected by the retina and intrinsically photosensitive retinal ganglion cells project this information both to the circadian system and limbic brain regions. Therefore, it is possible that exposure to light at night, which has become pervasive, may disrupt both circadian timing and mood. Notably, the rate of major depression has increased in recent decades, in parallel with increasing exposure to light at night. Strong evidence already links circadian disruption to major depression and other mood disorders. Emerging evidence from the past few years suggests that exposure to light at night also negatively influences mood. In this review, we discuss evidence from recent human and rodent studies supporting the novel hypothesis that nighttime exposure to light disrupts circadian organization and contributes to depressed mood.

Indexed as

AnimalsCircadian RhythmHumansLightingMood DisordersPhotoperiod

Identifiers

PMID23711982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.