Evidence map›Paper›PMID 23711436›Full record

ReviewCurrent opinion in chemical biology2013

Fluorescent probes for monitoring regulated secretion.

Wen-hong Li, Daliang Li

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Wen-hong LiDepartment of Cell Biology and of Biochemistry, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390-9039, United States. Wen-hong.li@utsouthwestern.edu
Daliang Li
The University of Texas Southwestern Medical Center · US

Funding

Cell Biology Research Improvements and RenovationsC06RR030414 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI FITZ, JOHN GREGORY · 2010 to 2010
$15.0M
Photonic probe and techniques for biological imaging applicationsR01GM077593 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI LI, WEN-HONG · 2006 to 2015
$2.7M
NCRR NIH HHS C06 RR030414NCRR NIH HHS C06 RR30414NIGMS NIH HHS R01 GM077593NIGMS NIH HHS R01-GM077593
6 · The paper itself

Abstract

Numerous secretory cells use the regulated secretory pathway to release signaling molecules. Regulated secretion is an essential component of the intercellular communication network of a multicellular organism and serves diverse functions in neurobiology, endocrinology, and many other aspects of animal physiology. Probes that can monitor a specific exocytotic event with high temporal and spatial resolution would be invaluable tools for studying the molecular and cellular mechanisms underlying stimulus-secretion coupling, and for characterizing secretion defects that are found in different human diseases. This review summarizes different strategies and recent progress in developing fluorescent sensors for imaging regulated cell secretion.

Indexed as

Adenosine TriphosphateAmino AcidsAnimalsExocytosisFluorescent DyesHumansZincAdenosine TriphosphateAmino AcidsFluorescent DyesZinc

Identifiers

PMID23711436
PMCPMC3742612
OpenAlexW2130218295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.