ArticleEvoDevo2013
Left-right asymmetric expression of dpp in the mantle of gastropods correlates with asymmetric shell coiling.
Article in EvoDevo, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 38 citations in OpenAlex.
- The physical basis of mollusk shell chiral coiling.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- The pond snail Lymnaea stagnalis.EvoDevo · 2020Review
- Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Growth and morphogenesis of the gastropod shell.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Insights into the Evolution of Shells and Love Darts of Land Snails Revealed from Their Matrix Proteins.Genome biology and evolution · 2019Article
- Article
- PfSMAD4 plays a role in biomineralization and can transduce bone morphogenetic protein-2 signals in the pearl oyster Pinctada fucata.BMC developmental biology · 2016Article
- A Whole Mount In Situ Hybridization Method for the Gastropod Mollusc Lymnaea stagnalis.Journal of visualized experiments : JoVE · 2016Article
- Sea shell diversity and rapidly evolving secretomes: insights into the evolution of biomineralization.Frontiers in zoology · 2016Review
- An optimised whole mount in situ hybridisation protocol for the mollusc Lymnaea stagnalis.BMC developmental biology · 2015Article
- Diversity and convergence in the mechanisms establishing L/R asymmetry in metazoa.EMBO reports · 2014Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious shapes of gastropod shells have evolved ever since the Cambrian. Although theoretical analyses of morphogenesis exist, the molecular basis of shell development remains unclear. We compared expression patterns of the decapentaplegic (dpp) gene in the shell gland and mantle tissues at various developmental stages between coiled-shell and non-coiled-shell gastropods.
resultsWe analyzed the expression patterns of dpp for the two limpets Patella vulgata and Nipponacmea fuscoviridis, and for the dextral wild-type and sinistral mutant lineage of the pond snail Lymnaea stagnalis. The limpets had symmetric expression patterns of dpp throughout ontogeny, whereas in the pond snail, the results indicated asymmetric and mirror image patterns between the dextral and sinistral lineages.
conclusionWe hypothesize that Dpp induces mantle expansion, and the presence of a left/right asymmetric gradient of the Dpp protein causes the formation of a coiled shell. Our results provide a molecular explanation for shell, coiling including new insights into expression patterns in post-embryonic development, which should aid in understanding how various shell shapes are formed and have evolved in the gastropods.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.