Trial reportTrials2013
Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT).
Trial report in Trials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 5 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Barriers and Facilitators to Implementing Cognitive Stimulation and Reminiscence Therapy for Dementia in Care Homes: Systematic Review.International journal of geriatric psychiatry · 2025Pooled it
- Technologies for Cognitive Training and Cognitive Rehabilitation for People With Mild Cognitive Impairment and Dementia. A Systematic Review.Frontiers in psychology · 2020Pooled it
- Cognitive training for people with mild to moderate dementia.The Cochrane database of systematic reviews · 2019Pooled it
- Goal setting and strategies to enhance goal pursuit for adults with acquired disability participating in rehabilitation.The Cochrane database of systematic reviews · 2015Pooled it
- Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia.The Cochrane database of systematic reviews · 2013Pooled it
- An intervention to promote self-management, independence and self-efficacy in people with early-stage dementia: the Journeying through Dementia RCT.Health technology assessment (Winchester, England) · 2022Trial
- Trial
- Impact of an intervention to support hearing and vision in dementia: The SENSE-Cog Field Trial.International journal of geriatric psychiatry · 2020Trial
- Improving hearing and vision in dementia: protocol for a field trial of a new intervention.BMJ open · 2017Trial
- Psychosocial therapy for Parkinson's-related dementia: study protocol for the INVEST randomised controlled trial.BMJ open · 2017Trial
- Cognitive rehabilitation for Parkinson’s disease dementia: a study protocol for a pilot randomised controlled trial.Trials · 2016Trial
- Article
- Engagement with behaviour change in people with mild cognitive impairment and mild frailty: a qualitative study.BMJ open · 2026Article
- Operationalizing goal setting as an outcome measure in trials involving patients with frailty, multimorbidity or complexity.Contemporary clinical trials communications · 2025Article
- Multisensory Stimulation in Rehabilitation of Dementia: A Systematic Review.Biomedicines · 2025Review
- Article
- Effectiveness of multifaceted interventions including motivational interviewing and home-based rehabilitation program for improving mental and physical health in stroke patients: A randomized controlled trial.International journal of nursing studies advances · 2024Article
- Efficacy and Feasibility of the CO-OP Approach in Parkinson's Disease: RCT Study Protocol.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2023Article
- Digital storytelling intervention to enhance social connections and participation for people with mild cognitive impairment: a research protocol.Frontiers in psychiatry · 2023Article
- Phytochemical Compounds and Nanoparticles as Phytochemical Delivery Systems for Alzheimer's Disease Management.Molecules (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundPreliminary evidence suggests that goal-oriented cognitive rehabilitation (CR) may be a clinically effective intervention for people with early-stage Alzheimer's disease, vascular or mixed dementia and their carers. This study aims to establish whether CR is a clinically effective and cost-effective intervention for people with early-stage dementia and their carers. METHODS/
designIn this multi-centre, single-blind randomised controlled trial, 480 people with early-stage dementia, each with a carer, will be randomised to receive either treatment as usual or cognitive rehabilitation (10 therapy sessions over 3 months, followed by 4 maintenance sessions over 6 months). We will compare the effectiveness of cognitive rehabilitation with that of treatment as usual with regard to improving self-reported and carer-rated goal performance in areas identified as causing concern by people with early-stage dementia; improving quality of life, self-efficacy, mood and cognition of people with early-stage dementia; and reducing stress levels and ameliorating quality of life for carers of participants with early-stage dementia. The incremental cost-effectiveness of goal-oriented cognitive rehabilitation compared to treatment as usual will also be examined. DISCUSSION: If the study confirms the benefits and cost-effectiveness of cognitive rehabilitation, it will be important to examine how the goal-oriented cognitive rehabilitation approach can most effectively be integrated into routine health-care provision. Our aim is to provide training and develop materials to support the implementation of this approach following trial completion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.