Evidence map›Paper›PMID 23710701›Full record

Observational studyRedox report : communications in free radical research2013

Effect of exercise on plasma paraoxonase1 activity in rugby players: dependance on training experience.

A Otocka-Kmiecik, K Bortnik, U Szkudlarek, D Nowak, M Orłowska-Majdak

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Redox report : communications in free radical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A Otocka-KmiecikDepartment of Experimental Physiology, Medical University of Lodz, Mazowiecka Street 6/8, Lodz, Poland. aneta.otocka-kmiecik@umed.lodz.pl
K Bortnik
U Szkudlarek
D Nowak
M Orłowska-Majdak
Medical University of Lodz · PLUniversity of Łódź · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere are conflicting data on the influence of physical activity on paraoxonase1 (PON1) activity. The purpose of this study is to investigate the effect of maximal exercise (ME) on plasma paraoxonase (PON) and arylesterase (ARE) activity in elite rugby players. In addition, the influence of training experience and PON1 Q192R polymorphism on PON1 activity changes at ME was evaluated.

methodsTwenty-five elite rugby players ages 22.0±3.71 years, consisting of 11 juniors--J (2-7 years of training) and 14 seniors--S (8-15 years of training), completed ME on a cycle ergometer. PON and ARE activity, ferric reducing activity of plasma (FRAP), uric acid (UA), and total bilirubin concentration, as well as thiobarbituric acid reactive substances and lipid profile were investigated in the plasma before, at the bout, and 30 minutes after ME.

resultsAt the bout of ME we found an increase in PON1 activities, ARE/high-density lipoprotein C ratio, TBil, and TChol. However, ARE activity changes were not observed in the group of rugby players training for ≤7 years. FRAP and UA increased later--30 minutes after ME.

conclusionWe conclude that in rugby players PON1 changes during ME depend on age, body composition, and training experience. The influence of PON1 Q192R polymorphism on PON1 changes at ME remains debatable.

Indexed as

AdultAntioxidantsAryldialkylphosphataseBilirubinCarboxylic Ester HydrolasesCholesterol, HDLErgometryExerciseFootballHumansNontherapeutic Human ExperimentationPolymorphism, GeneticThiobarbituric Acid Reactive SubstancesUric AcidYoung AdultAntioxidantsAryldialkylphosphatasearylesteraseBilirubinCarboxylic Ester HydrolasesCholesterol, HDLPON1 protein, humanThiobarbituric Acid Reactive SubstancesUric Acid

Identifiers

PMID23710701
PMCPMC6837636
OpenAlexW2149327139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.