Evidence map›Paper›PMID 23710463›Full record

ArticleBioMed research international2013

Sesame oil attenuates ovalbumin-induced pulmonary edema and bronchial neutrophilic inflammation in mice.

Dur-Zong Hsu, Chuan-Teng Liu, Pei-Yi Chu, Ya-Hui Li, Srinivasan Periasamy, Ming-Yie Liu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 40 citations in OpenAlex.

  1. β-glucan nanoparticles alleviate acute asthma by suppressing ferroptosis and DNA damage in mice.Apoptosis : an international journal on programmed cell death · 2025
    Article
  2. An Updated Comprehensive Review of Plants and Herbal Compounds with Antiasthmatic Effect.Evidence-based complementary and alternative medicine : eCAM · 2024
    Review
  3. Article
  4. Review
  5. Lipid Nutrition in Asthma.Cell biochemistry and biophysics · 2021
    Review
  6. Article
  7. A Review on WorldwideEvidence-based complementary and alternative medicine : eCAM · 2020
    Review
  8. Cyclic Peptide Extracts Derived FromFrontiers in pharmacology · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Inhibitory effect of sihuangxiechai decoction on ovalbumin-induced airway inflammation in Guinea pigs.Evidence-based complementary and alternative medicine : eCAM · 2014
    Article
  13. Type 1 diabetes, cardiovascular complications and sesame ( zhī má).Journal of traditional and complementary medicine · 2014
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dur-Zong HsuDepartment of Environmental and Occupational Health, National Cheng Kung University Medical College, 138 Sheng-Li Road, Tainan 70428, Taiwan.
Chuan-Teng Liu
Pei-Yi Chu
Ya-Hui Li
Srinivasan Periasamy
Ming-Yie Liu
National Cheng Kung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAllergic asthma is one of the most common chronic inflammatory diseases of airways. Severe asthma may lead to hospitalization and death. Sesame oil is a natural product with anti-inflammatory property. However, the effect of sesame oil on allergic asthma has never been studied.

objectiveWe investigate the effect of sesame oil on pulmonary inflammation in allergic asthma model.

methodsAllergic airway inflammation was induced by sensitizing with two doses of 10 mg ovalbumin (OVA) and then challenged with 1% OVA nebulizer exposure (1 h/day) for 3 days. Sesame oil (0.25, 0.5, or 1 mL/kg/day) was given orally 30 min before each challenge. Samples were collected 24 h after the last challenge.

resultsData showed that sesame oil inhibited pulmonary edema and decreased interleukin (IL)-1 β and IL-6 levels in bronchoalveolar lavage fluid in OVA-treated mice. Sesame oil also decreased pulmonary nitrite level, inducible nitric oxide synthase expression, and neutrophil infiltration induced by OVA. Further, sesame oil decreased serum IgE level in OVA-treated mice.

conclusionSesame oil may attenuate pulmonary edema and bronchial neutrophilic inflammation by inhibiting systemic IgE level in allergic asthma.

Indexed as

AnimalsAsthmaBronchoalveolar Lavage FluidDisease Models, AnimalGene Expression RegulationHumansHypersensitivityInterleukin-1betaInterleukin-6MiceNeutrophilsNitric Oxide Synthase Type IIOvalbuminPneumoniaPulmonary EdemaSesame OilInterleukin-1betaInterleukin-6Nitric Oxide Synthase Type IIOvalbuminSesame Oil

Identifiers

PMID23710463
PMCPMC3654634
OpenAlexW2029848947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.