Evidence map›Paper›PMID 23710459›Full record

ArticleBioMed research international2013

Engineering microbial cells for the biosynthesis of natural compounds of pharmaceutical significance.

Philippe Jeandet, Yann Vasserot, Thomas Chastang, Eric Courot

Abstract read
In one paragraph

Article in BioMed research international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Metabolic Engineering for Glycyrrhetinic Acid Production inFrontiers in bioengineering and biotechnology · 2020
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Antimicrobial activity of resveratrol analogues.Molecules (Basel, Switzerland) · 2014
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Philippe JeandetLaboratory of Enology and Applied Chemistry, Research Unit on Vines and Wines in Champagne, UPRES EA 4707, Faculty of Sciences, University of Reims, P.O. Box 1039, 51687 Reims Cedex 02, France. philippe.jeandet@univ-reims.fr
Yann Vasserot
Thomas Chastang
Eric Courot

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes constitute important platforms for the biosynthesis of numerous molecules of pharmaceutical interest such as antitumor, anticancer, antiviral, antihypertensive, antiparasitic, antioxidant, immunological agents, and antibiotics as well as hormones, belonging to various chemical families, for instance, terpenoids, alkaloids, polyphenols, polyketides, amines, and proteins. Engineering microbial factories offers rich opportunities for the production of natural products that are too complex for cost-effective chemical synthesis and whose extraction from their originating plants needs the use of many solvents. Recent progresses that have been made since the millennium beginning with metabolic engineering of microorganisms for the biosynthesis of natural products of pharmaceutical significance will be reviewed.

Indexed as

Cell EngineeringGenetic EngineeringAlkaloidsAnti-Bacterial AgentsBacteriaBiological ProductsBioreactorsHumansPolyketidesTerpenesAlkaloidsAnti-Bacterial AgentsBiological ProductsPolyketidesTerpenes

Identifiers

PMID23710459
PMCPMC3655478

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.