Evidence map›Paper›PMID 23710420›Full record

ArticleThe e-journal of neonatology research2012

Spontaneous Rhythmic Contractions (Vasomotion) of the Isolated, Pressurized Ductus Arteriosus of Preterm, but Not Term, Fetal Mice.

Megan Vucovich, Noah Ehinger, Stanley D Poole, Fred S Lamb, Jeff Reese

Abstract read
PubMed Full text at PMC
In one paragraph

Article in The e-journal of neonatology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. A novel role for PGEAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Megan VucovichVanderbilt University School of Medicine, Nashville, TN.
Noah Ehinger
Stanley D Poole
Fred S Lamb
Jeff Reese
Vanderbilt University · US

Funding

Genes contributing to patent ductus arteriosus susceptibility in preterm newbornsR01HL109199 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CLYMAN, RONALD I · 2011 to 2014
$3.0M
Mechanisms of Ductus Arteriosus RegulationR01HL077395 · NHLBI · VANDERBILT UNIVERSITY · PI REESE, JOHN JEFFREY · 2006 to 2010
$2.0M
Role of natriuretic peptides in the ductus arteriosusR01HL096967 · NHLBI · VANDERBILT UNIVERSITY · PI REESE, JOHN JEFFREY · 2010 to 2013
$1.5M
NHLBI NIH HHS R01 HL077395NHLBI NIH HHS R01 HL096967NHLBI NIH HHS R01 HL109199
6 · The paper itself

Abstract

The mechanisms that regulate relaxation of the fetal ductus arteriosus (DA) and its postnatal constriction are the subject of ongoing studies. Using pressure myography, a pattern of rhythmic oscillatory contractions termed vasomotion was observed in the isolated DA of preterm (day 15) fetal mice. Vasomotion was enhanced by oxygen-induced DA constriction and other contractile agents, and diminished by vasodilatory stimuli or inhibition of chloride channels. The DA of late preterm (day 17) or term (day 19) gestation fetal mice did not exhibit vasomotion. These studies establish the stage-specific presence of vasomotion in the DA of fetal mice and suggest that complex events contribute to intrinsic mechanisms for control of fetal DA tone.

Indexed as

chloride channelductus arteriosusmouseniflumic acidnitric oxidepretermprostaglandinvasomotion

Identifiers

PMID23710420
PMCPMC3661283
OpenAlexW2102984127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.