ArticleCommunicative & integrative biology2013
New insights into the protective power of platelets in malaria infection.
Article in Communicative & integrative biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Prevalence of thrombocytopenia among patients with malaria in Ethiopia: a systematic review and metanalysis.Malaria journal · 2025Pooled it
- Severe thrombocytopaenia in patients with vivax malaria compared to falciparum malaria: a systematic review and meta-analysis.Infectious diseases of poverty · 2018Pooled it
- Platelets as central hubs of inflammation.Frontiers in immunology · 2025Review
- Platelet Ido1 expression is induced during Plasmodium yoelii infection, altering plasma tryptophan metabolites.Blood advances · 2024Article
- Higher platelet counts and platelet factors are associated with a reduction in Plasmodium falciparum parasite density in young Malian children.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024Article
- Functional changes in hemostasis during asexual and sexual parasitemia in a controlled human malaria infection.PloS one · 2022Article
- Antimalarial and Erythrocyte Membrane Stability Properties ofInfection and drug resistance · 2021Article
- Role of Platelet Indices as a Potential Marker for Malaria Severity.Journal of parasitology research · 2021Review
- Multiplexed quantitative proteomics provides mechanistic cues for malaria severity and complexity.Communications biology · 2020Article
- Platelets beyond their count, as a key element of the innate immune system in the fight against malaria.British journal of haematology · 2020Article
- Patrolling the vascular borders: platelets in immunity to infection and cancer.Nature reviews. Immunology · 2019Review
- Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India.Malaria journal · 2019Article
- Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Platelets, as well as regulating blood hemostasis, are an important component of the body's defense against invading microbial pathogens. We previously reported that platelets protect during malaria infection by binding Plasmodium-infected erythrocytes (IE) and killing the parasite within. More recent studies have now revealed the platelet plasmocidal factor, platelet factor 4 (PF4) and the red cell-expressed Duffy-antigen molecule as the central players in the parasite killing activity of platelets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.