ArticleJournal of allergy2013
Role of obesity in asthma control, the obesity-asthma phenotype.
Article in Journal of allergy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 69 citations in OpenAlex.
- Mepolizumab reduces exacerbations in patients with severe eosinophilic asthma, irrespective of body weight/body mass index: meta-analysis of MENSA and MUSCA.Respiratory research · 2019Trial
- Evaluation of bronchial hyperresponsiveness in asthmatic paediatric patients using mannitol challenge test - Impacts of body mass index.Annals of medicine · 2025Article
- Clinical, radiological, and laboratory assessment of pulmonary eosinophilia syndrome: a case control study in Saudi Arabia.BMC pulmonary medicine · 2025Article
- The synergistic impact of sleep duration and obesity on metabolic syndrome risk: exploring the role of microRNAs.BioImpacts : BI · 2025Article
- Asthma and Hyperglycemia: Exploring the Interconnected Pathways.Diagnostics (Basel, Switzerland) · 2024Review
- Article
- Obesity-related biomarkers underlie a shared genetic architecture between childhood body mass index and childhood asthma.Communications biology · 2022Article
- Role of Obesity in Inflammation and Remodeling of Asthmatic Airway.Life (Basel, Switzerland) · 2022Review
- KRN7000 Reduces Airway Inflammation via Natural Killer T Cells in Obese Asthmatic Mice.Inflammation · 2021Article
- Prevalence of asymptomatic bronchiectasis and associations among the health screening population in South Korea.ERJ open research · 2021Article
- The Role of Nutritional Factors in Asthma: Challenges and Opportunities for Epidemiological Research.International journal of environmental research and public health · 2021Review
- Childhood Obesity and Respiratory Diseases: Which Link?Children (Basel, Switzerland) · 2021Review
- Correlation between oxidative stress and NF-κB signaling pathway in the obesity-asthma mice.Molecular biology reports · 2020Article
- Asthma medication in children who are overweight/obese: justified treatment?BMC pediatrics · 2019Observational
- Asthma, GERD and Obesity: Triangle of Inflammation.Indian journal of pediatrics · 2018Review
- Diet-induced obesity causes visceral, but not subcutaneous, lymph node hyperplasia via increases in specific immune cell populations.Cell proliferation · 2017Article
- Atopy, but not obesity is associated with asthma severity among children with persistent asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2016Article
- Obesity, Asthma, and Exercise in Child and Adolescent Health.Pediatric exercise science · 2016Article
- Correlation between oxidative stress and the NF-κB signaling pathway in the pulmonary tissues of obese asthmatic mice.Molecular medicine reports · 2016Article
- Assessment of asthma control using asthma control test in chest clinics in Cameroon: a cross-sectional study.The Pan African medical journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Asthma is a disease with distinct phenotypes that have implications for both prognosis and therapy. Epidemiologic studies have demonstrated an association between asthma and obesity. Further studies have shown that obese asthmatics have poor asthma control and more severe asthma. This obese-asthma group may represent a unique phenotype. The mechanisms behind poor asthma control in obese subjects remain unclear, but recent research has focused on adipokines and their effects on the airways as well as the role of oxidative stress. Both surgical and nonsurgical weight loss therapy have shown promising results with improvements in asthma control and decreased asthma severity. Comorbid conditions such as gastroesophageal reflux disease and obstructive sleep apnea may also have a role in poor asthma control in obese asthmatics. Further research is needed to define the mechanisms behind this phenotype which will guide the development of targeted therapies.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.