ArticleMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents2013
Synthesis and antimicrobial evaluation of some novel 1,2,4-triazole and 1,3,4-thiadiazole derivatives.
Article in Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Microwave-Assisted Organic Synthesis: An Eco-Friendly Method of Green Chemistry.Pharmaceuticals (Basel, Switzerland) · 2025Review
- A Comprehensive Review on Synthetic Approaches and Antibacterial Activity Studies of 1,2,4-Triazole Derivatives over the Past Sixteen Years (2009-Present).Current organic synthesis · 2025Review
- Hybrid Caffeic Acid-Based DHFR Inhibitors as Novel Antimicrobial and Anticancer Agents.Antibiotics (Basel, Switzerland) · 2024Article
- Synthesis and Antimicrobial Activity Screening of Piperazines BearingMolecules (Basel, Switzerland) · 2022Article
- Synthesis and cytotoxic activity evaluation of some new 1, 3, 4-oxadiazole, 1, 3, 4-thiadiazole and 1, 2, 4- triazole derivatives attached to phthalimide.Research in pharmaceutical sciences · 2021Article
- Article
- Synthesis and in vitro antimicrobial activity screening of new pipemidic acid derivatives.Archives of pharmacal research · 2018Article
- Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes.Chemistry Central journal · 2016Article
- Synthesis and biological evaluation of new pleuromutilin derivatives as antibacterial agents.Molecules (Basel, Switzerland) · 2014Article
- 4-[(5-Bromo-2-hy-droxy-benzyl-idene)amino]-3-ethyl-1H-1,2,4-triazole-5(4H)-thione.Acta crystallographica. Section E, Structure reports online · 2014Article
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Authors and funding
5 authors.
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Abstract
abstractThis study presents the synthesis and spectral analysis of new derivatives of 1,2,4-triazole-3-thione and 1,3,4-thiadiazole. New compounds were prepared by cyclization reaction of acyl thiosemicarbazide derivatives in the presence of alkaline and acidic media. All synthesized compounds were screened for their in vitro antibacterial activity by using the agar dilution technique. Six of the compounds had potential activity against Gram-positive bacteria (minimal inhibitory concentration [MIC] = 15.63-500 μg/mL). Some compounds showed good activity especially against GRAPHICAL ABSTRACT:
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