ArticleCold Spring Harbor perspectives in medicine2013
Current management of sickle cell anemia.
Article in Cold Spring Harbor perspectives in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 49 citations in OpenAlex.
- Psychometric evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS) in pediatric sickle cell disease in Europe.European journal of pediatrics · 2026Article
- Clinical and laboratory characteristics of adolescents and young adults with sickle cell disease at steady state in Uganda.PLOS global public health · 2026Article
- Efficacy of an Ayurvedic Intervention as an Adjunct to Standard Care in Preventing Acute Pain Crises in Sickle Cell Anemia: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Infectious Etiologies and Antimicrobial Management of Acute Chest Syndrome in Adult Sickle Cell Disease Patients: Pathogen Identification Patterns and Clinical Outcomes from a Five-Year Retrospective Study in Eastern Saudi Arabia.Pathogens (Basel, Switzerland) · 2025Article
- Article
- The epidemiology of very severe anaemia in sickle cell disease in Tanzania: a prospective cohort study.EClinicalMedicine · 2024Article
- Management of diabetes mellitus patients with sickle cell anemia: Challenges and therapeutic approaches.Medicine · 2024Review
- Article
- Review
- Low Stroke Risk in Children With Sickle Cell Disease in French Guiana: A Retrospective Cohort Study.Frontiers in medicine · 2022Article
- Calorimetric Characterisation of the Binding Reaction Between Human Ferric Haemoglobins and Haptoglobin to Develop a Drug for Removal of Cell-Free Haemoglobin.Advances in experimental medicine and biology · 2022Article
- Red blood cell exchange in children with sickle cell disease.International journal of hematology · 2022Article
- High fetal hemoglobin level is associated with increased risk of cerebral vasculopathy in children with sickle cell disease in Mayotte.BMC pediatrics · 2020Article
- Stress and the Home Environment in Caregivers of Children with Sickle Cell.Journal of pediatric psychology · 2020Article
- Spinal and afferent PKC signaling mechanisms that mediate chronic pain in sickle cell disease.Neuroscience letters · 2019Review
- Pediatric residents' perceived barriers to opioid use in sickle cell disease pain management.Pediatric blood & cancer · 2019Article
- Cost for sickle cell disease screening using isoelectric focusing with dried blood spot samples and estimation of price thresholds for a point-of-care test in Uganda.Journal of blood medicine · 2019Article
- Chronic Administration of Hydroxyurea (HU) Benefits Caucasian Patients with Sickle-Beta Thalassemia.International journal of molecular sciences · 2018Article
- Emerging point-of-care technologies for sickle cell disease screening and monitoring.Expert review of medical devices · 2016Review
- Initial Evaluation of the Pediatric PROMIS® Health Domains in Children and Adolescents With Sickle Cell Disease.Pediatric blood & cancer · 2016Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proper management of sickle cell anemia (SCA) begins with establishing the correct diagnosis early in life, ideally during the newborn period. The identification of affected infants by neonatal screening programs allows early initiation of prophylactic penicillin and pneumococcal immunizations, which help prevent overwhelming sepsis. Ongoing education of families promotes the early recognition of disease-released complications, which allows prompt and appropriate medical evaluation and therapeutic intervention. Periodic evaluation by trained specialists helps provide comprehensive care, including transcranial Doppler examinations to identify children at risk for primary stroke, plus assessments for other parenchymal organ damage as patients become teens and adults. Treatment approaches that previously highlighted acute vaso-occlusive events are now evolving to the concept of preventive therapy. Liberalized use of blood transfusions and early consideration of hydroxyurea treatment represent a new treatment paradigm for SCA management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.