Evidence map›Paper›PMID 23709506›Full record

ArticleApplied and environmental microbiology2013

Involvement of the novel two-component NsrRS and LcrRS systems in distinct resistance pathways against nisin A and nukacin ISK-1 in Streptococcus mutans.

Miki Kawada-Matsuo, Yuichi Oogai, Takeshi Zendo, Junichi Nagao, Yukie Shibata, Yoshihisa Yamashita, Yoshitoshi Ogura, Tetsuya Hayashi, Kenji Sonomoto, Hitoshi Komatsuzawa

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

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  18. Role ofThe Japanese dental science review · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Miki Kawada-MatsuoDepartment of Oral Microbiology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Yuichi Oogai
Takeshi Zendo
Junichi Nagao
Yukie Shibata
Yoshihisa Yamashita
Yoshitoshi Ogura
Tetsuya Hayashi
Kenji Sonomoto
Hitoshi Komatsuzawa
Kyushu University · JPKagoshima University · JPUniversity of Miyazaki · JPFukuoka Dental College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel two-component systems NsrRS and LcrRS are individually associated with resistance against the distinct lantibiotics nisin A and nukacin ISK-1 in Streptococcus mutans. NsrRS regulates the expression of NsrX, which is associated with nisin A binding, and LcrRS regulates the expression of the ABC transporter LctFEG.

Indexed as

Drug Resistance, BacterialATP-Binding Cassette TransportersBacteriocinsNisinOligonucleotide Array Sequence AnalysisStreptococcus mutansATP-Binding Cassette TransportersBacteriocinsNisinnisin Anukacin ISK-1

Identifiers

PMID23709506
PMCPMC3719517
OpenAlexW2029943202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.