Evidence map›Paper›PMID 23709437›Full record

Trial reportYonsei medical journal2013

Conservative and surgical treatment improves pain and ankle-brachial index in patients with lumbar spinal stenosis.

Seiji Ohtori, Masaomi Yamashita, Yasuaki Murata, Yawara Eguchi, Yasuchika Aoki, Hiromi Ataka, Jiro Hirayama, Tomoyuki Ozawa, Tatsuo Morinaga, Hajime Arai and 25 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Yonsei medical journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 1 institution in 1 country.

Seiji OhtoriDepartment of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan. sohtori@faculty.chiba-u.jp
Masaomi Yamashita
Yasuaki Murata
Yawara Eguchi
Yasuchika Aoki
Hiromi Ataka
Jiro Hirayama
Tomoyuki Ozawa
Tatsuo Morinaga
Hajime Arai
Masaya Mimura
Hiroto Kamoda
Sumihisa Orita
Masayuki Miyagi
Tomohiro Miyashita
Yuzuru Okamoto
Tetsuhiro Ishikawa
Hiroaki Sameda
Tomoaki Kinoshita
Eiji Hanaoka
Miyako Suzuki
Munetaka Suzuki
Takato Aihara
Toshinori Ito
Gen Inoue
Masatsune Yamagata
Tomoaki Toyone
Gou Kubota
Yoshihiro Sakuma
Yasuhiro Oikawa
Kazuhide Inage
Takeshi Sainoh
Kazuyo Yamauchi
Kazuhisa Takahashi
Chiba Low Back Pain Research Group
Chiba University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe pathological mechanism of lumbar spinal stenosis is reduced blood flow in nerve roots and degeneration of nerve roots. Exercise and prostaglandin E1 is used for patients with peripheral arterial disease to increase capillary flow around the main artery and improve symptoms; however, the ankle-brachial index (ABI), an estimation of blood flow in the main artery in the leg, does not change after treatment. Lumbar spinal nerve roots contain somatosensory, somatomotor, and unmyelinated autonomic nerves. Improved blood flow by medication with prostaglandin E1 and decompression surgery in these spinal nerve roots may improve the function of nerve fibers innervating muscle, capillary, and main vessels in the lower leg, resulting in an increased ABI. The purpose of the study was to examine whether these treatments can improve ABI. MATERIALS AND

methodsOne hundred and seven patients who received conservative treatment such as exercise and medication (n=56) or surgical treatment (n=51) were included. Low back pain and leg pain scores, walking distance, and ABI were measured before treatment and after 3 months of conservative treatment alone or surgical treatment followed by conservative treatment.

resultsLow back pain, leg pain, and walking distance significantly improved after both treatments (p<0.05). ABI significantly increased in each group (p<0.05).

conclusionThis is the first investigation of changes in ABI after treatment in patients with lumbar spinal stenosis. Improvement of the spinal nerve roots by medication and decompression surgery may improve the supply of blood flow to the lower leg in patients with lumbar spinal stenosis.

Indexed as

Ankle Brachial IndexAdultAgedAged, 80 and overAlprostadilDecompression, SurgicalFemaleHumansLow Back PainLumbar VertebraeMaleMiddle AgedPainSpinal Nerve RootsSpinal StenosisTreatment OutcomeAlprostadilAnkle-brachial indexlumbarpainspinal stenosis

Identifiers

PMID23709437
PMCPMC3663234
OpenAlexW2159292971

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.