Evidence map›Paper›PMID 23708912›Full record

ArticleLeukemia2013

NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes.

D M Murphy, R Bejar, K Stevenson, D Neuberg, Y Shi, C Cubrich, K Richardson, P Eastlake, G Garcia-Manero, H Kantarjian and 2 more

Abstract readLetter
In one paragraph

Article in Leukemia, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

D M MurphyDepartment of Radiation Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
R Bejar
K Stevenson
D Neuberg
Y Shi
C Cubrich
K Richardson
P Eastlake
G Garcia-Manero
H Kantarjian
B L Ebert
G Mike Makrigiorgos

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Tyrosine Kinases, Serine-Threonine Kinases,&Phosophatases in PathogenesisP01CA108631 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KORNBLAU, STEVEN M · 2005 to 2009
$9.7M
Functional Genomic Dissection of Refractory AnemiaR01HL082945 · NHLBI · DANA-FARBER CANCER INSTITUTE · PI EBERT, BENJAMIN LEVINE · 2005 to 2022
$6.8M
Characterization of Genetic Abnormalities in MDS and Their Clinical ImpactK08DK091360 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BEJAR, RAFAEL · 2012 to 2016
$789k
GENOME AMPLIFICATION TOLERANT TO SAMPLE DEGRADATIONR33CA111994 · NCI · DANA-FARBER CANCER INST · PI MAKRIGIORGOS, G. MIKE · 2007 to 2008
$656k
GENOME AMPLIFICATION TOLERANT TO SAMPLE DEGRADATIONR21CA111994 · NCI · DANA-FARBER CANCER INSTITUTE · PI MAKRIGIORGOS, G. MIKE · 2005 to 2006
$290k
High-throughput technology that enables sequencing depth for colorectal CAR21CA151164 · NCI · DANA-FARBER CANCER INST · PI MAKRIGIORGOS, G. MIKE · 2011 to 2012
$241k
NCI NIH HHS CA-111994NCI NIH HHS CA-151164NCI NIH HHS P01 CA108631NCI NIH HHS P01-CA108631NCI NIH HHS P30 CA016672NCI NIH HHS R21 CA111994NCI NIH HHS R21 CA151164NCI NIH HHS R33 CA111994NHLBI NIH HHS R01 HL082945NHLBI NIH HHS R01-HL082945NIDDK NIH HHS 1K08DK091360NIDDK NIH HHS K08 DK091360
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllelesDNA Mutational AnalysisDNA PrimersGTP PhosphohydrolasesHumansMembrane ProteinsMutationMyelodysplastic SyndromesPolymerase Chain ReactionPrognosisRisk FactorsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSurvival RateDNA PrimersGTP PhosphohydrolasesMembrane ProteinsNRAS protein, human

Identifiers

PMID23708912
PMCPMC3967719

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.