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Individualised treatment targets for elderly patients with type 2 diabetes using vildagliptin add-on or lone therapy (INTERVAL): a 24 week, randomised, double-blind, placebo-controlled study.
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FINDINGS: Between Dec 22, 2010, and March 14, 2012, we randomly assigned 139 patients each to the vildagliptin and placebo groups. 37 (27%) of 137 patients in the placebo group achieved their individualised targets by education and interactions with the study team alone and 72 (52.6%) of 137 patients achieved their target in the vildagliptin group (adjusted odds ratio 3.16, 96.2% CI 1.81-5.52; p<0.0001).
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FINDINGS: Between Dec 22, 2010, and March 14, 2012, we randomly assigned 139 patients each to the vildagliptin and placebo groups. 37 (27%) of 137 patients in the placebo group achieved their individualised targets by education and interactions with the study team alone and 72 (52.6%) of 137 patients achieved their target in the vildagliptin group (adjusted odds ratio 3.16, 96.2% CI 1.81-5.52; p<0.0001).