ArticleCell2013
Transitions for regulating early transcription.
Article in Cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- MYC: a complex problem.Trends in cell biology · 2023Review
- The regulation of transcription elongation in embryonic stem cells.Frontiers in cell and developmental biology · 2023Review
- Article
- MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation.Molecular cell · 2019Article
- Eukaryotic core promoters and the functional basis of transcription initiation.Nature reviews. Molecular cell biology · 2018Review
- Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle.Cell reports · 2017Article
- The intertwined roles of transcription and repair proteins.Molecular cell · 2013Review
- RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.Nucleus (Austin, Tex.)Review
- DNA topology and transcription.Nucleus (Austin, Tex.)Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene expression is largely regulated during the initiation of RNA polymerase II (PolII) transcription. In this issue, Kouzine et al. show that control of DNA melting is one of the critical rate-limiting steps for productive mRNA elongation. We discuss these findings in the context of other key energetic transitions.
Indexed as
Identifiers
23706732What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.