Evidence map›Paper›PMID 23706145›Full record

ArticleRadiation oncology (London, England)2013

Variability in prostate and seminal vesicle delineations defined on magnetic resonance images, a multi-observer, -center and -sequence study.

Tufve Nyholm, Joakim Jonsson, Karin Söderström, Per Bergström, Andreas Carlberg, Gunilla Frykholm, Claus F Behrens, Poul Flemming Geertsen, Redas Trepiakas, Scott Hanvey and 6 more

Abstract readMulticenter Study
In one paragraph

Article in Radiation oncology (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  18. Clinical workflow for MR-only simulation and planning in prostate.Radiation oncology (London, England) · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Tufve Nyholm
Joakim Jonsson
Karin Söderström
Per Bergström
Andreas Carlberg
Gunilla Frykholm
Claus F Behrens
Poul Flemming Geertsen
Redas Trepiakas
Scott Hanvey
Azmat Sadozye
Jawaher Ansari
Hazel McCallum
John Frew
Rhona McMenemin
Björn Zackrisson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of magnetic resonance (MR) imaging as a part of preparation for radiotherapy is increasing. For delineation of the prostate several publications have shown decreased delineation variability using MR compared to computed tomography (CT). The purpose of the present work was to investigate the intra- and inter-physician delineation variability for prostate and seminal vesicles, and to investigate the influence of different MR sequence settings used clinically at the five centers participating in the study.

methodsMR series from five centers, each providing five patients, were used. Two physicians from each center delineated the prostate and the seminal vesicles on each of the 25 image sets. The variability between the delineations was analyzed with respect to overall, intra- and inter-physician variability, and dependence between variability and origin of the MR images, i.e. the MR sequence used to acquire the data.

resultsThe intra-physician variability in different directions was between 1.3 - 1.9 mm and 3 - 4 mm for the prostate and seminal vesicles respectively (1 std). The inter-physician variability for different directions were between 0.7 - 1.7 mm and approximately equal for the prostate and seminal vesicles. Large differences in variability were observed for individual patients, and also for individual imaging sequences used at the different centers. There was however no indication of decreased variability with higher field strength.

conclusionThe overall delineation variability is larger for the seminal vesicles compared to the prostate, due to a larger intra-physician variability. The imaging sequence appears to have a large influence on the variability, even for different variants of the T2-weighted spin-echo based sequences, which were used by all centers in the study.

Indexed as

HumansMagnetic Resonance ImagingMaleObserver VariationProstatic NeoplasmsRadiotherapy Planning, Computer-AssistedSeminal Vesicles

Identifiers

PMID23706145
PMCPMC3680182

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