Evidence map›Paper›PMID 23705959›Full record

ArticleCardiovascular diabetology2013

Sex-specific-differences in cardiometabolic risk in type 1 diabetes: a cross-sectional study.

Alexandra Kautzky-Willer, Kathrin Stich, Juliane Hintersteiner, Alexander Kautzky, Majid Reza Kamyar, Johannes Saukel, Julienne Johnson, Rosa Lemmens-Gruber

Open access · goldFull text read
In one paragraph

Article in Cardiovascular diabetology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 51 citations in OpenAlex.

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  12. Multimorbidity Among Adult Outpatients With Type 1 Diabetes in Germany.Journal of diabetes science and technology · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. A Compendium of Perspectives on Diabetes: A Challenge for Sustainable Health in the Modern Era.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Review
  18. Review
  19. Article
  20. Statin Adherence: Does Gender Matter?Current atherosclerosis reports · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Alexandra Kautzky-WillerGender Medicine Unit, Department of Internal Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. alexandra.kautzky-willer@meduniwien.ac.at
Kathrin Stich
Juliane Hintersteiner
Alexander Kautzky
Majid Reza Kamyar
Johannes Saukel
Julienne Johnson
Rosa Lemmens-Gruber
University of Vienna · ATMedical University of Vienna · ATUniversity of Strathclyde · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the impact of sex-specific differences in the management of type 1 diabetes (T1DM). Thus, we evaluated the influence of gender on risk factors, complications, clinical care and adherence in patients with T1DM.

methodsIn a cross-sectional study, sex-specific disparities in glycaemic control, cardiovascular risk factors, diabetic complications, concomitant medication use and adherence to treatment recommendations were evaluated in 225 consecutive patients (45.3% women) who were comparable with respect to age, diabetes duration, and body mass index.

resultsAlthough women with T1DM had a higher total cholesterol than men, triglycerides were higher in obese men and males with HbA1c>7% than in their female counterparts. No sex differences were observed in glycaemic control and in micro- or macrovascular complications. However, the subgroup analysis showed that nephropathy was more common in obese men, hyperlipidaemic women and all hypertensive patients, whereas peripheral neuropathy was more common in hyperlipidaemic women. Retinopathy was found more frequently in women with HbA1c>7%, obese men and in both sexes with a long duration of diabetes. The multivariate analysis revealed that microvascular complications were associated with the duration of disease and BMI in both sexes and with hyperlipidaemia in males. The overall adherence to interventions according to the guidelines was higher in men than in women. This adherence was concerned particularly with co-medication in patients diagnosed with hypertension, aspirin prescription in elderly patients and the achievement of target lipid levels following the prescription of statins.

conclusionsOur data showed sex differences in lipids and overweight in patients with T1DM. Although glycaemic control and the frequency of diabetic complications were comparable between the sexes, the overall adherence to guidelines, particularly with respect to the prescription of statins and aspirin, was lower in women than in men.

Indexed as

AdultAspirinBlood PressureCardiovascular DiseasesCross-Sectional StudiesDiabetes ComplicationsDiabetes Mellitus, Type 1Diabetic NephropathiesDiabetic RetinopathyDrug MonitoringFemaleGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemiasHypertensionAspirinHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic AgentsPlatelet Aggregation Inhibitors

Identifiers

PMID23705959
PMCPMC3666903
OpenAlexW2124782592

What OpenQuestion holds

Textfull text, public
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.