ArticleMolecular cancer2013
Raman imaging at biological interfaces: applications in breast cancer diagnosis.
Article in Molecular cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Raman and surface-enhanced Raman spectroscopy for intraoperative cancer diagnostics: sentinel lymph node biopsy, biomarkers and translational challenges.Frontiers in bioengineering and biotechnology · 2026Review
- AI-assisted SERS imaging method for label-free and rapid discrimination of clinical lymphoma.Journal of nanobiotechnology · 2025Article
- Exploring druggable targets and inflammation-mediated pathways in cancer: a Mendelian randomization analysis integrating transcriptomic and proteomic data.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Enhancing spectral imaging with multi-condition image fusion.Scientific reports · 2025Article
- Differentiation of Salivary Gland and Salivary Gland Tumor Tissue via Raman Imaging Combined with Multivariate Data Analysis.Diagnostics (Basel, Switzerland) · 2023Article
- Smart and low-cost fluorometer for identifying breast cancer malignancy based on lipid droplets accumulation.PloS one · 2023Article
- Building an ensemble learning model for gastric cancer cell line classification via rapid raman spectroscopy.Computational and structural biotechnology journal · 2023Article
- Assessment of TiOMaterials (Basel, Switzerland) · 2022Article
- Design and Development of a Bimodal Optical Instrument for Simultaneous Vibrational Spectroscopy Measurements.International journal of molecular sciences · 2022Article
- Intraoperative detection of human meningioma using a handheld visible resonance Raman analyzer.Lasers in medical science · 2022Article
- Design and evaluation of Raman reporters for the Raman-silent region.Nanotheranostics · 2022Article
- Lipid profiling using Raman and a modified support vector machine algorithm.Journal of Raman spectroscopy : JRS · 2021Article
- Differential Membrane Lipid Profiles and Vibrational Spectra of Three Edaphic Algae and One Cyanobacterium.International journal of molecular sciences · 2021Article
- Label-Free Infrared Spectroscopic Imaging Reveals Heterogeneity of β-Sheet Aggregates in Alzheimer's Disease.The journal of physical chemistry letters · 2021Article
- Telomere Length Shortening in Microglia: Implication for Accelerated Senescence and Neurocognitive Deficits in HIV.Vaccines · 2021Article
- Iron-binding cellular profile of transferrin using label-free Raman hyperspectral imaging and singular value decomposition (SVD).Free radical biology & medicine · 2021Article
- Cancerous Tissue Diagnosis by LIF Spectroscopy Derived From Body-Compatible Fluorophores.Journal of lasers in medical sciences · 2021Article
- Nitrogen-Doped Titanium Dioxide Nanoparticles Modified by An Electron Beam for Improving Human Breast Cancer Detection by Raman Spectroscopy: A Preliminary Study.Diagnostics (Basel, Switzerland) · 2020Article
- Discrimination of Benign and Malignant Lesions in Canine Mammary Tissue Samples Using Raman Spectroscopy: A Pilot Study.Animals : an open access journal from MDPI · 2020Article
- Vibrational Spectroscopy Fingerprinting in Medicine: from Molecular to Clinical Practice.Materials (Basel, Switzerland) · 2019Review
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4 authors.
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Abstract
backgroundOne of the most important areas of Raman medical diagnostics is identification and characterization of cancerous and noncancerous tissues. The methods based on Raman scattering has shown significant potential for probing human breast tissue to provide valuable information for early diagnosis of breast cancer. A vibrational fingerprint from the biological tissue provides information which can be used to identify, characterize and discriminate structures in breast tissue, both in the normal and cancerous environment.
resultsThe paper reviews recent progress in understanding structure and interactions at biological interfaces of the human tissue by using confocal Raman imaging and IR spectroscopy. The important differences between the noncancerous and cancerous human breast tissues were found in regions characteristic for vibrations of carotenoids, fatty acids, proteins, and interfacial water. Particular attention was paid to the role played by unsaturated fatty acids and their derivatives as well as carotenoids and interfacial water.
conclusionsWe demonstrate that Raman imaging has reached a clinically relevant level in regard to breast cancer diagnosis applications. The results presented in the paper may have serious implications on understanding mechanisms of interactions in living cells under realistically crowded conditions of biological tissue.
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