SynthesisBMC surgery2013
Laparoscopic surgery for Crohn's disease: a meta-analysis of perioperative complications and long term outcomes compared with open surgery.
Synthesis in BMC surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- The outcomes of robotic ileocolic resection in Crohn's disease compared with laparoscopic and open surgery: a meta-analysis and systematic review.Techniques in coloproctology · 2025Pooled it
- What have we learned in minimally invasive colorectal surgery from NSQIP and NIS large databases? A systematic review.International journal of colorectal disease · 2018Pooled it
- Trial
- Laparoscopic surgery is associated with reduced long-term reoperation risk in Crohn's disease.Techniques in coloproctology · 2026Article
- Ileocecal resection for primary Crohn's disease: a 17-year experience from a tertiary care hospital in North Africa.Crohn's & colitis 360 · 2026Article
- Robotic versus laparoscopic surgery for IBD: a case-matched comparison during the learning curve.Updates in surgery · 2026Article
- Timing of ileocolic resection for Crohn's disease: A survey of the patient perspective in the 'biological' era.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Comparative anastomotic configurations and disease recurrence rates of robotic vs. laparoscopic primary ileocolonic resection for Crohn's disease.Surgical endoscopy · 2026Article
- Understanding the therapeutic toolkit for inflammatory bowel disease.Nature reviews. Gastroenterology & hepatology · 2025Review
- Optimizing Biologic Therapy for the Prevention of Post-Operative Recurrence in Crohn's Disease: Current Evidence and Future Perspectives.Biomedicines · 2025Review
- Substantial Reduction of Systemic Corticosteroid Use After Primary Ileocaecal Resection in Swedish Patients With Crohn's Disease: A Population-Based Cohort Study.Alimentary pharmacology & therapeutics · 2025Article
- Current approaches to the surgical management of Crohn's disease in Australia and New Zealand.International journal of colorectal disease · 2025Article
- The Relationship between the Psoas Muscle Mass Index and Postoperative Complications in Crohn's Disease: A Retrospective Cohort Study.Journal of the anus, rectum and colon · 2025Article
- Management of inflammatory bowel disease in the emergency setting: the MIBODI international survey and evidence-based practices.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Clinical Significance of Prognostic Nutrition Index in Patients with Crohn's Disease after Primary Bowel Resection.Yonsei medical journal · 2024Article
- Risk and management of post-operative infectious complications in inflammatory bowel disease: A systematic review.World journal of gastrointestinal surgery · 2023Article
- Clinical and surgical factors for successful stoma reversal in patients with Crohn's disease-results of a retrospective cohort study.International journal of colorectal disease · 2022Article
- Revisiting fibrosis in inflammatory bowel disease: the gut thickens.Nature reviews. Gastroenterology & hepatology · 2022Review
- Short-term and long-term outcomes of laparoscopicWorld journal of gastroenterology · 2021Article
- The Revival of Surgery in Crohn's Disease-Early Intestinal Resection as a Reasonable Alternative in Localized Ileitis.Biomedicines · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundPrevious meta-analyses have had conflicting conclusions regarding the differences between laparoscopic and open techniques in patients with Crohn's Disease. The objective of this meta-analysis was to compare outcomes in patients with Crohn's disease undergoing laparoscopic or open surgical resection.
methodsA literature search of EMBASE, MEDLINE, The Cochrane Central Register of Controlled Trials and the US National Institute of Health's Clinical Trials Registry was completed. Randomized clinical trials and non-randomized comparative studies were included if laparoscopic and open surgical resections were compared. Primary outcomes assessed included perioperative complications, recurrence requiring surgery, small bowel obstruction and incisional hernia.
results34 studies were included in the analysis, and represented 2,519 patients. Pooled analysis showed reduced perioperative complications in patients undergoing laparoscopic resection vs. open resection (Risk Ratio 0.71, 95% CI 0.58 - 0.86, P = 0.001). There was no evidence of a difference in the rate of surgical recurrence (Rate Ratio 0.78, 95% CI 0.54 - 1.11, P = 0.17) or small bowel obstruction (Rate Ratio 0.63, 95% CI 0.28 - 1.45, P = 0.28) between techniques. There was evidence of a decrease in incisional hernia following laparoscopic surgery (Rate Ratio 0.24, 95% CI 0.07 - 0.82, P = 0.02).
conclusionsThis is the largest review in this topic. The results of this analysis are based primarily on non-randomized studies and thus have significant limitations in regards to selection bias, confounding, lack of blinding and potential publication bias. Although we found evidence of decreased perioperative complications and incisional hernia in the laparoscopic group, further randomized controlled trials, with adequate follow up, are needed before strong recommendations can be made.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.