ArticleBMC public health2013
Modifiable exposures to air pollutants related to asthma phenotypes in the first year of life in children of the EDEN mother-child cohort study.
Article in BMC public health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 26 citations in OpenAlex.
- Exposure to Disinfectants and Cleaning Products and Respiratory Health of Workers and Children in Daycares: The CRESPI Cohort Protocol.International journal of environmental research and public health · 2023Article
- Associations of Preconception Exposure to Air Pollution and Greenness with Offspring Asthma and Hay Fever.International journal of environmental research and public health · 2020Article
- Indoor mould exposure, asthma and rhinitis: findings from systematic reviews and recent longitudinal studies.European respiratory review : an official journal of the European Respiratory Society · 2018Review
- Pollution and respiratory disease: can diet or supplements help? A review.Respiratory research · 2018Review
- Wood Stove Pollution in the Developed World: A Case to Raise Awareness Among Pediatricians.Current problems in pediatric and adolescent health care · 2017Review
- Air Pollution During Pregnancy and Cord Blood Immune System Biomarkers.Journal of occupational and environmental medicine · 2016Article
- Outdoor air pollution and asthma.Lancet (London, England) · 2014Review
- Host and environmental predictors of exhaled breath temperature in the elderly.BMC public health · 2013Article
- Epigenomics and allergic disease.Epigenomics · 2013Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies have shown diverse strength of evidence for the associations between air pollutants and childhood asthma, but these associations have scarcely been documented in the early life. The purpose of this study was to evaluate the impacts of various air pollutants on the development of asthma phenotypes in the first year of life.
methodsAdjusted odds ratios were estimated to assess the relationships between exposures to air pollutants and single and multi-dimensional asthma phenotypes in the first year of life in children of the EDEN mother-child cohort study (n = 1,765 mother-child pairs). The Generalized Estimating Equation (GEE) model was used to determine the associations between prenatal maternal smoking and in utero exposure to traffic-related air pollution and asthma phenotypes (data were collected when children were at birth, and at 4, 8 and 12 months of age). Adjusted Population Attributable Risk (aPAR) was estimated to measure the impacts of air pollutants on health outcomes.
resultsIn the first year of life, both single and multi-dimensional asthma phenotypes were positively related to heavy parental smoking, traffic-related air pollution and dampness, but negatively associated with contact with cats and domestic wood heating. Adjusted odds ratios (aORs) for traffic-related air pollution were the highest [1.71 (95% Confidence Interval (CI): 1.08-2.72) for ever doctor-diagnosed asthma, 1.44 (95% CI: 1.05-1.99) for bronchiolitis with wheezing, 2.01 (95% CI: 1.23-3.30) for doctor-diagnosed asthma with a history of bronchiolitis]. The aPARs based on these aORs were 13.52%, 9.39%, and 17.78%, respectively. Results persisted for prenatal maternal smoking and in utero exposure to traffic-related air pollution, although statistically significant associations were observed only with the asthma phenotype of ever bronchiolitis.
conclusionsAfter adjusting for potential confounders, traffic-related air pollution in utero life and in the first year of life, had a greater impact on the development of asthma phenotypes compared to other factors.
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