ArticleOrthopedic reviews2013
Conservative management of symptomatic knee osteoarthritis: a flawed strategy?
Article in Orthopedic reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy: Effectiveness of 5 Nerve Protocols Versus 3 Nerve and 2 Nerve Protocols - A Prospective Randomized Controlled Study
Super Selective Angiographic Catheterization and Embolization of Genicular Arteries for Treatment of Symptomatic Knee Osteoarthritis
Who cites it
59 citing papers in PubMed, 5 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Transarterial Embolization in Osteoarthritis of the Knee: Mechanism of Action and Current Results.Deutsches Arzteblatt international · 2026Pooled it
- Mesenchymal stem cell-derived exosomes for the treatment of knee osteoarthritis: a systematic review and meta-analysis based on rat model.Frontiers in pharmacology · 2025Pooled it
- Effectiveness of Internet-Based Telehealth Programs in Patients With Hip or Knee Osteoarthritis: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Pooled it
- Pooled it
- Effects of Transcranial Direct Current Stimulation and Individualized Physical Therapy on Pain and Function in Individuals With Chronic Knee Pain: A Pilot Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Trial
- Effectiveness of genicular nerve block on pain and disability in chronic knee osteoarthritis: a randomized double blinded placebo controlled trial.Clinical rheumatology · 2026Trial
- Trial
- Cryoneurolysis for the management of chronic pain in patients with knee osteoarthritis; a double-blinded randomized controlled sham trial.BMC musculoskeletal disorders · 2021Trial
- Effectiveness of intra-articular injections of sodium bicarbonate and calcium gluconate in the treatment of osteoarthritis of the knee: a randomized double-blind clinical trial.BMC musculoskeletal disorders · 2015Trial
- Outcomes of Medial Open Wedge High Tibial Osteotomy in a University Hospital.Malaysian orthopaedic journal · 2026Article
- Article
- Exosomes in Osteoarthritis: Emerging Roles in Pathogenesis, Diagnosis, and Therapeutic Potential.Current pharmaceutical design · 2026Review
- Patient perceptions of physiotherapy and prehabilitation before hip and knee arthroplasty in South Africa.African journal of disability · 2026Article
- Review
- Postprocedure protocols after intraarticular orthobiologic injections-A scoping review.PM & R : the journal of injury, function, and rehabilitation · 2025Article
- Simultaneous Bilateral Total Knee Arthroplasty in a Post-Traumatic Osteoarthritis Patient: A Case Report and Literature Review.Clinical case reports · 2025Article
- Genicular Artery Embolization in Moderate to Severe Knee Osteoarthritis: Technique, Safety and Clinical Outcome.Cardiovascular and interventional radiology · 2025Article
- Quality of Non-Surgical and Non-Pharmacological Knee Osteoarthritis Care in the Maritimes.Musculoskeletal care · 2025Observational
- Efficacy of Genicular Nerve Block in Patients with Osteoarthritis: A Comparative Study with and without Fluoroscopy Assistance.Revista brasileira de ortopedia · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conservative management of medial compartment knee osteoarthritis (OA) is a misleading term used to describe the application of medical, orthotic, and/or rehabilitative therapies exclusive of surgical interventions. The implication of this nomenclature is that these therapies offer satisfactory symptom relief, alter disease progression, and have limited side effects. Unfortunately, conservative therapeutic options possesses few, if any, characteristics of an ideal treatment, namely one that significantly alleviates pain, improves knee function, and reduces medial compartmental loading without adverse side effects. As uncompensated mechanical loading is a primary culprit in the development and progression of knee OA, we propose that the therapeutic perspective of conservative treatment should shift from pharmacological treatments, which have no influence on joint loading, minimal potential to alter joint function, substantial associated risks, and significant financial costs, towards minimally invasive load absorbing therapeutic interventions. A safe and effective minimally invasive medical device specifically engineered for symptomatic relief of medial knee OA by limiting joint contact forces has the potential to reduce the clinical and economic knee OA burden. This review characterizes the current standard of care recommendations for conservative management of medial compartment knee OA with respect to treatment efficacy, risk profile, and economic burden.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.