ArticleDiabetic foot & ankle2013
Etiology, pathophysiology and classifications of the diabetic Charcot foot.
Article in Diabetic foot & ankle, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 87 citations in OpenAlex.
- Fibrillin-1 alleviates high glucose-induced fibroblast apoptosis and inflammation via autophagy activation.Nutrition & diabetes · 2026Article
- Combined Circulating microRNA and Inflammatory Cytokine Profiles Improve Disease-Stage Discrimination of Charcot Foot in Egyptian Patients with Type 2 Diabetes Mellitus.Biomedicines · 2026Article
- Forefoot Charcot Neuroarthropathy following Forefoot Surgery in a Non-Diabetic Patient with Myelopathy: A Rare Presentation not to be Missed.Journal of orthopaedic case reports · 2026Article
- Charcot foot disease: A new approach.Drugs & aging · 2025Review
- Article
- Electrodiagnostic evidence of nerve regeneration in patients with diabetic Charcot foot treated with proximal tibial cortex transverse distraction.Joint diseases and related surgery · 2025Article
- PATHOGENESIS OF ACUTE DIABETIC CHARCOT ARTHROPATHY IN THE FOOT AND ANKLE: A COMPREHENSIVE LITERATURE REVIEW.Orthopedic reviews · 2025Article
- What the Physician Needs to Know about Charcot Arthropathy and Ankle Fracture Treatment Dilemma: A Case Report and a Possible Medical Approach and Treatment Algorithm.Journal of orthopaedic case reports · 2024Article
- Establishment of a Neurodegenerative Charcot Mouse Model.Foot & ankle international · 2023Article
- Review
- Correlation analysis between foot deformity and diabetic foot with radiographic measurement.Frontiers in clinical diabetes and healthcare · 2023Article
- Ankle arthritis - an important signpost in rheumatologic practice.Rheumatology (Oxford, England) · 2021Review
- Ocular Manifestations and Neuropathy in Type 2 Diabetes Patients With Charcot Arthropathy.Frontiers in endocrinology · 2021Observational
- Midterm Fate of the Contralateral Foot in Charcot Arthropathy.Foot & ankle international · 2020Article
- Managing diabetic foot in times of COVID-19: time to put the best 'foot' forward.International journal of diabetes in developing countries · 2020Review
- Comments on the Article "Results of Simple Conservative Treatment of Midfoot Charcot Arthropathy": In Reply.Clinics in orthopedic surgery · 2020Article
- Microscopic study of chronic charcot arthropathy foot bones contributes to understanding pathogenesis - A preliminary report.Histology and histopathology · 2020Article
- Multi-System Factors Associated with Metatarsophalangeal Joint Deformity in Individuals with Type 2 Diabetes.Journal of clinical medicine · 2020Article
- A radiological severity scale to measure the impact of Charcot's Neuroarthropathy: an observational study.Journal of foot and ankle research · 2020Observational
- Pulmonary Function Tests and Their Associated Factors Among Type 2 Diabetic Patients at Jimma Medical Center, in 2019; Comparative Cross-Sectional Study.International journal of general medicine · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In people with diabetes mellitus, the Charcot foot is a specific manifestation of peripheral neuropathy that may involve autonomic neuropathy with high blood flow to the foot, leading to increased bone resorption. It may also involve peripheral somatic polyneuropathy with loss of protective sensation and high risk of unrecognized acute or chronic minor trauma. In both cases, there is excess local inflammatory response to foot injury, resulting in local osteoporosis. In the Charcot foot, the acute and chronic phases have been described. The former is characterized by local erythema, edema, and marked temperature elevation, while pain is not a prominent symptom. In the latter, signs of inflammation gradually recede and deformities may develop, increasing the risk of foot ulceration. The most common anatomical classification describes five patterns, according to the localization of bone and joint pathology. This review article aims to provide a brief overview of the diabetic Charcot foot in terms of etiology, pathophysiology, and classification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.