Evidence map›Paper›PMID 23705028›Full record

ArticlePloS one2013

Evaluation and correction for optical scattering variations in laser speckle rheology of biological fluids.

Zeinab Hajjarian, Seemantini K Nadkarni

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zeinab HajjarianWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
Seemantini K Nadkarni
Harvard University · US

Funding

Rapid Fluorescence-Based Determination of Antibiotic SusceptibilityU54EB015408 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI PARRISH, JOHN A, SCHACHTER, STEVEN · 2012 to 2022
$49.2M
Blood Coagulation Monitoring at the Point of CareR01HL119867 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NADKARNI, SEEMANTINI K · 2014 to 2018
$2.2M
Intracoronary Laser Speckle Imaging for Atherosclerotic Plaque DiagnosisR21HL088306 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NADKARNI, SEEMANTINI K · 2008 to 2009
$755k
NHLBI NIH HHS R01 HL119867NHLBI NIH HHS R21 HL 088306NHLBI NIH HHS R21 HL088306NHLBI NIH HHS R21 HL 088306-02S1NIBIB NIH HHS U54 EB015408NIBIB NIH HHS U54 EB015408-01
6 · The paper itself

Abstract

Biological fluids fulfill key functionalities such as hydrating, protecting, and nourishing cells and tissues in various organ systems. They are capable of these versatile tasks owing to their distinct structural and viscoelastic properties. Characterizing the viscoelastic properties of bio-fluids is of pivotal importance for monitoring the development of certain pathologies as well as engineering synthetic replacements. Laser Speckle Rheology (LSR) is a novel optical technology that enables mechanical evaluation of tissue. In LSR, a coherent laser beam illuminates the tissue and temporal speckle intensity fluctuations are analyzed to evaluate mechanical properties. The rate of temporal speckle fluctuations is, however, influenced by both optical and mechanical properties of tissue. Therefore, in this paper, we develop and validate an approach to estimate and compensate for the contributions of light scattering to speckle dynamics and demonstrate the capability of LSR for the accurate extraction of viscoelastic moduli in phantom samples and biological fluids of varying optical and mechanical properties.

Indexed as

LasersLightScattering, RadiationAlgorithmsAnimalsBody FluidsCattleElastic ModulusGlycerolPhotonsRheologySynovial FluidTitaniumViscosityVitreous BodyWaterGlycerolTitaniumtitanium dioxideWater

Identifiers

PMID23705028
PMCPMC3660338
OpenAlexW2141913030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.