ArticlePloS one2013
Relationship between ultrasound backscattered statistics and the concentration of fatty droplets in livers: an animal study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Ultrasound derived fat fraction indicates reduction of liver fat content after lifestyle modification in obese patients.Clinical hemorheology and microcirculation · 2025Article
- Changes in mechanical properties at the muscle level could be detected by Nakagami imaging during in-vivo fixed-end contractions.PloS one · 2024Article
- Information Entropy and Its Applications.Advances in experimental medicine and biology · 2023Article
- Quantitative Evaluation of Hepatic Steatosis Using Advanced Imaging Techniques: Focusing on New Quantitative Ultrasound Techniques.Korean journal of radiology · 2022Review
- Detection of pediatric hepatic steatosis through ultrasound backscattering analysis.European radiology · 2021Article
- Ultrasound Assessment of Hepatic Steatosis by Using the Double Nakagami Distribution: A Feasibility Study.Diagnostics (Basel, Switzerland) · 2020Article
- Multimodal imaging reveals transient liver metabolic disturbance and sinusoidal circulation obstruction after a single administration of ketamine/xylazine mixture.Scientific reports · 2020Article
- Performance Evaluations on Using Entropy of Ultrasound Log-Compressed Envelope Images for Hepatic Steatosis Assessment: An In Vivo Animal Study.Entropy (Basel, Switzerland) · 2018Article
- Small-window parametric imaging based on information entropy for ultrasound tissue characterization.Scientific reports · 2017Article
- Article
- Multifeature analysis of an ultrasound quantitative diagnostic index for classifying nonalcoholic fatty liver disease.Scientific reports · 2016Article
- Ultrasound characterization of the mastoid for detecting middle ear effusion: A preliminary clinical validation.Scientific reports · 2016Article
- A Computer-Aided Diagnosis Scheme For Detection Of Fatty Liver In Vivo Based On Ultrasound Kurtosis Imaging.Journal of medical systems · 2016Article
- Entropic imaging of cataract lens: an in vitro study.PloS one · 2014Article
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Authors and funding
6 authors.
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Abstract
Ultrasound grayscale B-mode imaging is the most frequently used modality for examining fatty liver. Different concentrations and arrangements of fatty droplets in the liver may produce different statistical distributions of ultrasound backscatter signals, which may be treated as a useful clue for assessing the stage of fatty liver. To verify this point, we investigate the relationship between changes in backscattered statistics and the concentration of fatty droplets in the liver. Fatty liver was induced in rats fed a methionine-choline-deficient diet. Livers were excised from rats for in vitro ultrasound scanning using a single-element transducer. The envelopes of the acquired raw ultrasound signals were used for the analysis of the backscattered statistics by ultrasound Nakagami parametric imaging, which has been shown as a reliable tool to model the statistical distribution of ultrasound backscatter signals. Histological analyses and the measurements of triglyceride and cholesterol in the rat liver were conducted for comparison with the Nakagami parameter. Results show that the ultrasound Nakagami parameter has an excellent correlation with the concentration of fatty droplets, demonstrating that ultrasound backscatter statistics depend on the degree of fatty liver in rats.
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