Trial reportAnnals of oncology : official journal of the European Society for Medical Oncology2013
Efficacy of multimodal exercise-based rehabilitation on physical activity, cardiorespiratory fitness, and patient-reported outcomes in cancer survivors: a randomized, controlled trial.
Trial report in Annals of oncology : official journal of the European Society for Medical Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04679233 (Feasibility and Preliminary Efficacy of Aerobic Exercise in Head and Neck Cancer Patients Undergoing Radiation Therapy), which is not on this map. Cited by 23 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Preliminary Efficacy of Aerobic Exercise in Head and Neck Cancer Patients Undergoing Radiation Therapy
Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023Pooled it
- Attention to principles of exercise training: an updated systematic review of randomized controlled trials in cancers other than breast and prostate.BMC cancer · 2021Pooled it
- Effects of high-intensity training on the quality of life of cancer patients and survivors: a systematic review with meta-analysis.Scientific reports · 2021Pooled it
- Multidisciplinary Outpatient Cancer Rehabilitation Can Improve Cancer Patients' Physical and Psychosocial Status-a Systematic Review.Current oncology reports · 2020Pooled it
- Aerobic physical exercise for adult patients with haematological malignancies.The Cochrane database of systematic reviews · 2019Pooled it
- Efficacy of Exercise Therapy on Cardiorespiratory Fitness in Patients With Cancer: A Systematic Review and Meta-Analysis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018Pooled it
- Self-monitoring physical activity with a smartphone application in cancer patients: a randomized feasibility study (SMART-trial).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Trial
- A 3-week multimodal intervention involving high-intensity interval training in female cancer survivors: a randomized controlled trial.Physiological reports · 2016Trial
- Efficacy of walking or exercise for improving perceived cognitive function in adults during and after cancer therapy: a systematic review and network analysis.Journal of cancer survivorship : research and practice · 2026Review
- Nutritional and Exercise Interventions in Cancer-Related Cachexia: An Extensive Narrative Review.International journal of environmental research and public health · 2022Review
- Vertebral fracture during one repetition maximum testing in a breast cancer survivor: A case report.Medicine · 2021Article
- A Group-Based 8-Week Functional Interval-Type Outdoor Training Program Improves Physical Performance in Recreationally Active Adults.Frontiers in sports and active living · 2021Article
- Rationale and design of a randomised controlled trial investigating the effect of multidisciplinary nutritional rehabilitation for patients treated for head and neck cancer (the NUTRI-HAB trial).Nutrition journal · 2020Article
- Cancer and Exercise: Warburg Hypothesis, Tumour Metabolism and High-Intensity Anaerobic Exercise.Sports (Basel, Switzerland) · 2018Review
- Exercise for people with cancer: a systematic review.Current oncology (Toronto, Ont.) · 2017Review
- Oncology care provider perspectives on exercise promotion in people with cancer: an examination of knowledge, practices, barriers, and facilitators.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Exercise for people with cancer: a clinical practice guideline.Current oncology (Toronto, Ont.) · 2017Article
- Assessment of Cancer Survivors' Experiences of Using a Publicly Available Physical Activity Mobile Application.JMIR cancer · 2016Article
- Interval versus continuous aerobic exercise training in breast cancer survivors--a pilot RCT.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
- Diet, exercise, obesity, smoking and alcohol consumption in cancer survivors and the general population: a comparative study of 16 282 individuals.British journal of cancer · 2015Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSedentary behavior and impaired cardiovascular reserve capacity are common late effects of cancer therapy emphasizing the need for effective strategies to increase physical activity (PA) in cancer survivors. We examined the efficacy of a 12-month exercise-based rehabilitation program on self-reported PA, cardiorespiratory fitness (VO2peak), strength, and patient-reported outcomes. PATIENTS AND
methodsTwo hundred fourteen post-treatment cancer survivors were randomly assigned to a 12-month rehabilitation program consisting of individual (x3) and group-based (x6) counseling in combination with once weekly high-intensity group-based exercise training (the Copenhagen Physical Activity after Cancer Treatment, PACT; n = 108) or to a health evaluation program (HE, n = 106). Study outcomes were assessed at baseline, 6 months, and 12 months.
resultsAfter 12 months, the percentage of patients reporting meeting PA goal behavior (≥3 h/week) was significantly increased in the PACT group versus the HE group (70.4% versus 43.4%, P = 0.001). Repeated measures analyses indicated a statistically significant improvement in VO2peak (l min(-1)) in favour of PACT (treatment effect ratio = 1.04; 95% confidence interval 1.00-1.07; P = 0.032). Significant between group differences were also observed for strength (P < 0.001), depression (P = 0.020) and mental health (P = 0.040).
conclusionA 12-month exercise-based rehabilitation program is an effective strategy to promote PA and improve VO2peak in cancer survivors.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.