Evidence map›Paper›PMID 23703730›Full record

Trial reportNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2013

Pilot randomized controlled trial of web-based acceptance and commitment therapy for smoking cessation.

Jonathan Bricker, Christopher Wyszynski, Bryan Comstock, Jaimee L Heffner

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03351712 (ACTonHEALTH Study Protocol), which is not on this map. Cited by 91 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03351712 naunknown statusnot on this mapstarted 2020, after this paper: background citation

ACTonHEALTH Study Protocol: Promoting Psychological Flexibility With Activity Tracker and mHealth Tools to Foster Healthy Lifestyle for Obesity and Other Chronic Health Conditions

TypeinterventionalSponsorIstituto Auxologico ItalianoRan2020 to 2024Enrolled60ConditionsHealth BehaviorArmsACT-Based Intervention and Activity Tracker WITH Feedback, Gold Standard Intervention + Activity Tracker WITHOUT Feedback, Gold Standard Intervention and Activity Tracker WITH Feedback, ACT-Based Intervention and Activity Tracker WITHOUT Feedback
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Internet-based interventions for smoking cessation.The Cochrane database of systematic reviews · 2017
    Pooled it
  4. Pooled it
  5. Trial
  6. ACT on Vaping: Pilot Randomized Controlled Trial of a Novel Digital Health App With Text Messaging for Young Adult Vaping Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
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  13. Efficacy and Utilization of Smartphone Applications for Smoking Cessation Among American Indians and Alaska Natives: Results From the iCanQuit Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Trial
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  19. Craving to Quit: A Randomized Controlled Trial of Smartphone App-Based Mindfulness Training for Smoking Cessation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Trial
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jonathan BrickerPublic Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA;
Christopher Wyszynski
Bryan Comstock
Jaimee L Heffner

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
Randomized Trial of Web-Delivered Acceptance Therapy for Smoking CessationR01CA166646 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BRICKER, JONATHAN B · 2013 to 2017
$3.4M
Targeted Intervention for Bipolar SmokersK23DA026517 · NIDA · UNIVERSITY OF CINCINNATI · PI HEFFNER, JAIMEE · 2009 to 2013
$654k
NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA166646NCI NIH HHS R01CA166646 01A1NIDA NIH HHS K23 DA026517NIDA NIH HHS K23DA026517
6 · The paper itself

Abstract

objectiveWeb-based smoking cessation interventions have high reach, but low effectiveness. To address this problem, we conducted a pilot randomized controlled trial of the first web-based acceptance and commitment therapy (ACT) intervention for smoking cessation. The aims were to determine design feasibility, user receptivity, effect on 30-day point prevalence quit rate at 3 months post-randomization, and mediation by ACT theory-based processes of acceptance.

methodsAdult participants were recruited nationally into the double-blind randomized controlled pilot trial (N = 222), which compared web-based ACT for smoking cessation (WebQuit.org) with the National Cancer Institute's Smokefree.gov-the U.S. national standard for web-based smoking cessation interventions.

resultsWe recruited 222 participants in 10 weeks. Participants spent significantly longer on the ACT WebQuit.org site per login (18.98 vs. 10.72 min; p = .001) and were more satisfied with the site (74% vs. 42%; p =.002). Using available follow-up data, more than double the fraction of participants in the ACT WebQuit.org arm had quit smoking at the 3-month follow-up (23% vs. 10%; OR = 3.05; 95% CI = 1.01-9.32; p = .050). Eighty percent of this effect was mediated by ACT theory-based increases in total acceptance of physical, cognitive, and emotional cues to smoke (p < .001).

conclusionsThe trial design was feasible. Compared with Smokefree.gov, ACT had higher user receptivity and short-term cessation, and strong evidence of theory-based mechanisms of change. While results were promising, they were limited by the pilot design (e.g., limited follow-up), and thus a full-scale efficacy trial is now being conducted.

Indexed as

InternetDouble-Blind MethodFemaleHumansMaleSmoking Cessation

Identifiers

PMID23703730
PMCPMC3768336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.