ReviewCurrent opinion in nephrology and hypertension2013
The function of endocytosis in podocytes.
Review in Current opinion in nephrology and hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity.Nature communications · 2019Pooled it
- Roles of myosin 1e and the actin cytoskeleton in kidney functions and familial kidney disease.Cytoskeleton (Hoboken, N.J.) · 2024Review
- Inhibition of p38 MAPK decreases hyperglycemia-induced nephrin endocytosis and attenuates albuminuria.Journal of molecular medicine (Berlin, Germany) · 2022Article
- Podocyte Endocytosis in Regulating the Glomerular Filtration Barrier.Frontiers in medicine · 2022Review
- Identification of Podocyte Cargo Proteins by Proteomic Analysis of Clathrin-Coated Vesicles.Kidney360 · 2020Article
- Exocyst Genes Are Essential for Recycling Membrane Proteins and Maintaining Slit Diaphragm inJournal of the American Society of Nephrology : JASN · 2020Article
- Rethinking Lupus Nephritis Classification on a Molecular Level.Journal of clinical medicine · 2019Article
- The lysosomal disease caused by mutant VPS33A.Human molecular genetics · 2019Article
- Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus.PloS one · 2018Article
- Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes.Cellular and molecular life sciences : CMLS · 2017Article
- Role of albumin and its modifications in glomerular injury.Pflugers Archiv : European journal of physiology · 2017Review
- APOL1-G1 in Nephrocytes Induces Hypertrophy and Accelerates Cell Death.Journal of the American Society of Nephrology : JASN · 2017Article
- APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes.Journal of the American Society of Nephrology : JASN · 2017Article
- A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease.PloS one · 2017Article
- Podocyte-actin dynamics in health and disease.Nature reviews. Nephrology · 2016Review
- Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD.Journal of the American Society of Nephrology : JASN · 2016Article
- Shank2 Regulates Renal Albumin Endocytosis.Physiological reports · 2015Article
- Effects of FSGS-associated mutations on the stability and function of myosin-1 in fission yeast.Disease models & mechanisms · 2015Article
- Podocin is translocated to cytoplasm in puromycin aminonucleoside nephrosis rats and in poor-prognosis patients with IgA nephropathy.Cell and tissue research · 2015Article
- Review series: The cell biology of renal filtration.The Journal of cell biology · 2015Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewIn this review, we discuss the role of endocytosis, a fundamental process internalizing molecules from the plasma membrane, and its critical importance in podocyte biology. RECENT
findingsEndocytic clathrin and nonclathrin-coated pits have been visualized in podocytes using electron microscopy, but the functional biological relevance has not been well defined. Recent evidence suggests that loss of key clathrin endocytic regulatory apparatus, such as dynamin, synaptojanin 1 or endophilin, in genetic mouse models of disease results in severe proteinuria and foot process effacement. In addition, several genes implicated in human nephrotic syndrome directly or indirectly associate with these endocytic proteins, thus creating a protein network that is linked in actin dynamics, signalling and endocytosis. SUMMARY: This review summarizes our current understanding of membrane trafficking specifically in podocytes, thus giving further novel insights into the molecular mechanisms and pathogenesis of nephrotic syndrome.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.