ArticleThe Indian journal of medical research2013
Serological & molecular approaches for diagnosis of leptospirosis in a tertiary care hospital in north India: a 10-year study.
Article in The Indian journal of medical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Leptospirosis and its co-infections in India: prevalence, geographic distribution, and clinical implications.BMC infectious diseases · 2026Pooled it
- Leptospirosis in Central Romania: A 17-Year Single-Center Cohort Study of Hospitalized Adults.Microorganisms · 2026Article
- Endemicity, Clinical Features, Risk Factors, and the Potential for Severe Infection inTropical medicine and infectious disease · 2025Article
- Epidemiological Features of Leptospirosis and Identification ofInfectious disease reports · 2024Article
- Rickettsial Infections Are Neglected Causes of Acute Febrile Illness in Teluk Intan, Peninsular Malaysia.Tropical medicine and infectious disease · 2022Article
- Etiologic Agents of Fever of Unknown Origin Among Patients Attending Mnazi Mmoja Hospital, Zanzibar.Journal of community health · 2020Article
- Hepatitis E Virus Induced Acute Liver Failure with Scrub Typhus Coinfection in a Pregnant Woman.Journal of clinical and experimental hepatology · 2017Article
- Clinical Evaluation of Rapid Diagnostic Test Kit Using the Polysaccharide as a Genus-Specific Diagnostic Antigen for Leptospirosis in Korea, Bulgaria, and Argentina.Journal of Korean medical science · 2016Article
- Leptospirosis in pigs, dogs, rodents, humans, and water in an area of the Colombian tropics.Tropical animal health and production · 2014Article
- Diagnosis of leptospirosis.The Indian journal of medical research · 2013Article
- Authors' response.The Indian journal of medical research · 2013Article
- Serological evidence of human leptospirosis in patients with acute undifferentiated febrile illness from Uttarakhand, India: A pilot study.Journal of laboratory physiciansArticle
- Decreasing trend of seroprevalence of leptospirosis at All India Institute of Medical Sciences New Delhi: 2014-2018.Journal of family medicine and primary careArticle
- Utility of Loop-mediated Isothermal Amplification Assay, Polymerase Chain Reaction, and ELISA for Diagnosis of Leptospirosis in South Indian Patients.Journal of global infectious diseasesArticle
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7 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
objectivesLeptospirosis, a spirochetal zoonosis, is underreported from the northern States of India. This study reports results of a 10-year retrospective sero-epidemiological survey of leptospirosis conducted in a tertiary care hospital in New Delhi, India.
methodA total of 1453 patients clinically suspected for leptospirosis were included and investigated initially by IgM ELISA. A proportion of these were subjected to culture, microscopic agglutination test (MAT) and polymerase chain reaction (PCR).
resultsOf the 1453 patients, 391 (26.90%) were positive serologically by IgM ELISA. Seropositive and seronegative patients revealed no significant difference in clinical features and laboratory parameters. Amongst the IgM seropositive cases, culture for leptospires was positive in 5 of 192 (2.6%), MAT in 50 of 138 (36.23%), PCR from blood and urine in 10 of 115 (8.7%) and 10 of 38 (26.31%) cases, respectively. In Leptospira spp. positive patients co-infections with viral hepatitis E, malaria and dengue fever were diagnosed in 27 cases. INTERPRETATION &
conclusionsThe overall seropositivity for leptospirosis was 26.9 per cent in our study. A decreasing trend in seropositivity was observed in recent years. Co-infections with malaria, dengue, hepatitis A and E were also seen. Since leptospirosis is a treatable disease, correct and rapid diagnosis may help in effective management of patients.
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23703348PMC3724261W1951400902What OpenQuestion holds
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