ReviewEndocrinology and metabolism clinics of North America2013
Diabetes and altered glucose metabolism with aging.
Review in Endocrinology and metabolism clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 111 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
BAT as a Therapeutic for the Metabolic and Cardiac Dysfunction With Senescence Pilot
Fasting to Provide Energy Needed to Help Adults in Need of Cognitive Enhancement (FASTING ENHANCE)
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Telomere Length in Peripheral Blood Leukocytes A Follow-up Pilot Study
Who cites it
111 citing papers in PubMed, 3 syntheses or guidelines pooled it, 206 citations in OpenAlex.
- Risk prediction model for cognitive frailty in older adults with diabetes: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Glycemic impact of non-nutritive sweeteners: a systematic review and meta-analysis of randomized controlled trials.European journal of clinical nutrition · 2018Pooled it
- Management of Diabetes in Long-term Care and Skilled Nursing Facilities: A Position Statement of the American Diabetes Association.Diabetes care · 2016Guideline
- The effect of a low renal acid load diet on blood pressure, lipid profile, and blood glucose indices in patients with type 2 diabetes: a randomized clinical trial.Nutrition journal · 2023Trial
- Weight Loss and Exercise Differentially Affect Insulin Sensitivity, Body Composition, Cardiorespiratory Fitness, and Muscle Strength in Older Adults With Obesity: A Randomized Controlled Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022Trial
- Pharmacokinetics and Glucodynamics of Ultra Rapid Lispro (URLi) versus HumalogClinical pharmacokinetics · 2020Trial
- Short-term time-restricted feeding is safe and feasible in non-obese healthy midlife and older adults.GeroScience · 2020Trial
- A Comparison of Pharmacokinetic and Pharmacodynamic Properties Between Faster-Acting Insulin Aspart and Insulin Aspart in Elderly Subjects with Type 1 Diabetes Mellitus.Drugs & aging · 2017Trial
- Habitual fasting duration and accelerated multimorbidity in older adults.Journal of internal medicine · 2026Article
- Article
- Comparative performance of insulin resistance-related indices in predicting adverse cardiovascular events among individuals with NAFLD and MASLD: a multi-center cohort study.Cardiovascular diabetology · 2026Observational
- The association between glucose dynamics and energy intake in young, healthy women.European journal of clinical nutrition · 2026Article
- Does Aging Affect Diet-Induced Thermogenesis? Revisiting the Evidence from Human Studies.Current obesity reports · 2026Review
- Polypharmacy Reflects Metabolic Burden Rather than Frailty in Older Adults with Type 2 Diabetes: A Comprehensive Geriatric Assessment Study.Journal of clinical medicine · 2026Article
- Latent biochemical phenotypes delineate divergent health trajectories in older adults.npj aging · 2026Article
- Article
- Aging-Induced QT Prolongation as a Potential Contributor to Longevity.Journal of cardiovascular development and disease · 2026Review
- Comparative evaluation of insulin resistance indices for predicting adverse cardiovascular events in hyperuricemia: insights from UK biobank and Shanghai Pudong cohort.Frontiers in nutrition · 2026Article
- GLP-1 Receptor Agonist Therapy and Cardiorenal Outcomes in Patients ≥ 80 Years Old With Type 2 Diabetes.Journal of the American Geriatrics Society · 2026Article
- PTEN regulates vagal-insulin signaling to optimize autonomic output determining peripheral inflammatory and metabolic homeostasis.Nature communications · 2025Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Diabetes and impaired glucose tolerance affect a substantial proportion of older adults. Abnormal glucose metabolism is not a necessary component of aging. Older adults with diabetes and altered glucose status likely represent a subset of the population at high risk for complications and adverse geriatric syndromes. Goals for treatment of diabetes in the elderly include control of hyperglycemia, prevention and treatment of diabetic complications, avoidance of hypoglycemia, and preservation of quality of life. Research exploring associations of dysglycemia and insulin resistance with the development of adverse outcomes in the elderly may ultimately inform use of future glucose-lowering therapies in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.