ArticleJournal of biological dynamics2013
A deterministic model for influenza infection with multiple strains and antigenic drift.
Article in Journal of biological dynamics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Dynamics of two-strain influenza model with cross-immunity and no quarantine class.Journal of mathematical biology · 2016Article
- The Role of Serotype Interactions and Seasonality in Dengue Model Selection and Control: Insights from a Pattern Matching Approach.PLoS neglected tropical diseases · 2016Article
- Forecasting the 2013-2014 influenza season using Wikipedia.PLoS computational biology · 2015Article
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Authors and funding
3 authors.
Funding
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Abstract
We describe a multiple strain Susceptible Infected Recovered deterministic model for the spread of an influenza subtype within a population. The model incorporates appearance of new strains due to antigenic drift, and partial immunity to reinfection with related circulating strains. It also includes optional seasonal forcing of the transmission rate of the virus, which allows for comparison between temperate zones and the tropics. Our model is capable of reproducing observed qualitative patterns such as the overall annual outbreaks in the temperate region, a reduced magnitude and an increased frequency of outbreaks in the tropics, and the herald wave phenomenon. Our approach to modelling antigenic drift is novel and further modifications of this model may help improve the understanding of complex influenza dynamics.
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