Evidence map›Paper›PMID 23700966›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2013

Preterm birth time trends in Europe: a study of 19 countries.

J Zeitlin, K Szamotulska, N Drewniak, A D Mohangoo, J Chalmers, L Sakkeus, L Irgens, M Gatt, M Gissler, B Blondel and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02929953 (Prevalence of Premature Birth History Among Type 1 Diabetes Mellitus), which is not on this map. Cited by 132 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
132citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02929953 completednot on this mapstarted 2014, after this paper: background citation

Prevalence of Premature Birth History Among Type 1 Diabetes Mellitus (T1D) Patients and Characteristics of Premature Born Children Who Develop T1D Compared With Those Who do Not

TypeobservationalSponsorAssaf Harofeh MCRan2014 to 2019Enrolled3,600ConditionsType 1 Diabetes MellitusArmschart review
3 · Its place in the literature

Who cites it

132 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  13. External validation of QUiPP App in three independent European cohorts of symptomatic women.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025
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72 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

J ZeitlinINSERM, UMRS 953, Epidemiological Research Unit on Perinatal and Women's and Children's Health, Paris, France; UPMC, Paris, France.
K Szamotulska
N Drewniak
A D Mohangoo
J Chalmers
L Sakkeus
L Irgens
M Gatt
M Gissler
B Blondel
Euro-Peristat Preterm Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate time trends in preterm birth in Europe by multiplicity, gestational age, and onset of delivery.

designAnalysis of aggregate data from routine sources.

settingNineteen European countries. POPULATION: Live births in 1996, 2000, 2004, and 2008.

methodsAnnual risk ratios of preterm birth in each country were estimated with year as a continuous variable for all births and by subgroup using log-binomial regression models.

main outcome measuresOverall preterm birth rate and rate by multiplicity, gestational age group, and spontaneous versus non-spontaneous (induced or prelabour caesarean section) onset of labour.

resultsPreterm birth rates rose in most countries, but the magnitude of these increases varied. Rises in the multiple birth rate as well as in the preterm birth rate for multiple births contributed to increases in the overall preterm birth rate. About half of countries experienced no change or decreases in the rates of singleton preterm birth. Where preterm birth rates rose, increases were no more prominent at 35-36 weeks of gestation than at 32-34 weeks of gestation. Variable trends were observed for spontaneous and non-spontaneous preterm births in the 13 countries with mode of onset data; increases were not solely attributed to non-spontaneous preterm births.

conclusionsThere was a wide variation in preterm birth trends in European countries. Many countries maintained or reduced rates of singleton preterm birth over the past 15 years, challenging a widespread belief that rising rates are the norm. Understanding these cross-country differences could inform strategies for the prevention of preterm birth.

Indexed as

EuropeFemaleGestational AgeHumansInfant, NewbornLive BirthMultiple Birth OffspringPregnancyPremature BirthEuropeindicated preterm birthsmultiple birthspreterm birthstime trends

Identifiers

PMID23700966
PMCPMC4285908

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.