ArticleAdipocyte2012
New insights into adipocyte-specific leptin gene expression.
Article in Adipocyte, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 37 citations in OpenAlex.
- Metreleptin therapy for nonalcoholic steatohepatitis: Open-label therapy interventions in two different clinical settings.Med (New York, N.Y.) · 2021Trial
- Adipogenesis Under Leptin Control: Mechanisms and Model-Specific Effects.International journal of molecular sciences · 2026Review
- Effects of Dapagliflozin on Myocardial Gene Expression in BTBR Mice with Type 2 Diabetes.Cardiovascular drugs and therapy · 2025Article
- Transcriptional and epigenetic changes after dietary and surgical weight loss interventions in an animal model of obesity.International journal of obesity (2005) · 2024Article
- Visceral Adipose Tissue Bioenergetics Varies According to Individuals' Obesity Class.International journal of molecular sciences · 2023Article
- Recent Advances in the Knowledge of the Mechanisms of Leptin Physiology and Actions in Neurological and Metabolic Pathologies.International journal of molecular sciences · 2023Review
- Dynamics of transcriptome and chromatin accessibility revealed sequential regulation of potential transcription factors during the brown adipose tissue whitening in rabbits.Frontiers in cell and developmental biology · 2022Article
- Regulation of lymphatic function and injury by nitrosative stress in obese mice.Molecular metabolism · 2020Article
- Egr1 loss-of-function promotes beige adipocyte differentiation and activation specifically in inguinal subcutaneous white adipose tissue.Scientific reports · 2020Article
- Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production.Scientific reports · 2019Article
- Metabolic Association between Leptin and the Corticotropin Releasing Hormone.Endocrine, metabolic & immune disorders drug targets · 2019Article
- Leptin and brain-adipose crosstalks.Nature reviews. Neuroscience · 2018Review
- Collagen overlays can inhibit leptin and adiponectin secretion but not lipid accumulation in adipocytes.PeerJ · 2018Article
- Article
- Satietogenic Protein from Tamarind Seeds Decreases Food Intake, Leptin Plasma and CCK-1r Gene Expression in Obese Wistar Rats.Obesity facts · 2018Article
- Maternal pre-pregnancy BMI downregulates neonatal cord blood LEP methylation.Pediatric obesity · 2017Article
- Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner.Molecular metabolism · 2017Article
- Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival.Molecular metabolism · 2016Article
- Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression.World journal of gastroenterology · 2016Article
- Leptin, IL-6, and suPAR reflect distinct inflammatory changes associated with adiposity, lipodystrophy and low muscle mass in HIV-infected patients and controls.Immunity & ageing : I & A · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The adipocyte-derived hormone leptin is a critical regulator of many physiological functions, ranging from satiety to immunity. Surprisingly, very little is known about the transcriptional pathways that regulate adipocyte-specific expression of leptin. In a recent published study, we pursued a strategy integrating BAC transgenic reporter mice, in vitro reporter assays, and chromatin state mapping to locate an adipocyte-specific cis-element upstream of the
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.