ReviewObesity surgery2013
Challenges in the optimisation of post-operative pain management with opioids in obese patients: a literature review.
Review in Obesity surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Efficacy of Erector Spinae Plane Block on Analgesic Outcomes in Patients Undergoing Metabolic Surgery: A Meta-Analysis of Randomized Controlled Trials.Obesity surgery · 2025Pooled it
- Surgical transversus abdominis plane block with liposomal bupivacaine at cesarean: a pilot randomized trial.American journal of obstetrics & gynecology MFM · 2024Trial
- Trial
- Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial.American journal of obstetrics & gynecology MFM · 2021Trial
- Magnesium Sulfate Reduced Opioid Consumption in Obese Patients Undergoing Sleeve Gastrectomy: a Prospective, Randomized Clinical Trial.Obesity surgery · 2018Trial
- Liberal Fluid Therapy Increases Postoperative Acute Kidney Injury in Patients Undergoing Laparoscopic Sleeve Gastrectomy with Dexmedetomidine.Obesity surgery · 2025Article
- The association of obesity with post-cesarean inpatient opioid consumption.International journal of obesity (2005) · 2024Article
- Propensity score matched analysis of postoperative nausea and pain after one anastomosis gastric bypass (MGB/OAGB) versus sleeve gastrectomy (SG).Updates in surgery · 2023Article
- The effect of body mass index on thoracic paravertebral block analgesia after video-assisted thoracoscopic surgery; a prospective interventional study.BMC anesthesiology · 2023Article
- Opioid Analgesics after Bariatric Surgery: A Scoping Review to Evaluate Physiological Risk Factors for Opioid-Related Harm.Journal of clinical medicine · 2023Article
- Postoperative Respiratory Compromise following Cesarean Birth: The Impact of Obesity and Systemic Opioids.AJP reports · 2022Article
- Association of Physical Therapy Interventions With Long-term Opioid Use After Total Knee Replacement.JAMA network open · 2021Article
- OpiTrack: A Wearable-based Clinical Opioid Use Tracker with Temporal Convolutional Attention Networks.Proceedings of the ACM on interactive, mobile, wearable and ubiquitous technologies · 2021Article
- The impact of obesity and smoking on young individuals suffering from lumbar disc herniation: a retrospective analysis of 97 cases.Neurosurgical review · 2020Article
- Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy.Obesity surgery · 2020Article
- Drug- and alcohol-related mortality risk after bariatric surgery: evidence from a 7-year prospective multicenter cohort study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019Article
- Provider preferences for postoperative analgesia in obese and non-obese patients undergoing ambulatory surgery.Journal of pharmaceutical policy and practice · 2018Article
- Use of prescribed opioids before and after bariatric surgery: prospective evidence from a U.S. multicenter cohort study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2017Observational
- Perioperative Analgesia for Fast-Track Laparoscopic Bariatric Surgery.Obesity surgery · 2017Observational
- Preoperative Slow-Release Morphine Reduces Need of Postoperative Analgesics and Shortens Hospital Stay in Laparoscopic Gastric Bypass.Obesity surgery · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing number of obese patients are undergoing surgery, particularly bariatric and orthopaedic surgery. The physiological differences between obese and normal-weight subjects may modify not only anaesthetic requirements during surgery but also post-operative analgesic management, raising a number of challenges in a critical period. In this review, we analyse studies of post-operative pain management with opioids in obese subjects. We discuss the genetic factors common to pain and obesity and the factors potentially modifying opioid pharmacokinetics and pharmacodynamics in obese patients, and we analyse the overall efficacy and safety of opioids for pain management during the post-operative period in obese patients. Both modifications to surgical methods and additional analgesic treatments to decrease the requirement for opioids may improve early rehabilitation and quality of care and reduce adverse effects in obese patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.