SynthesisFamilial cancer2013
Screening participation for people at increased risk of colorectal cancer due to family history: a systematic review and meta-analysis.
Synthesis in Familial cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
- Trial
- Invitation to Screening Colonoscopy in the Population at Familial Risk for Colorectal Cancer.Deutsches Arzteblatt international · 2018Trial
- Trial
- Evaluation of serum nucleoside diphosphate kinase A for the detection of colorectal cancer.Scientific reports · 2016Trial
- Interest and informational preferences regarding genomic testing for modest increases in colorectal cancer risk.Public health genomics · 2014Trial
- Article
- Development and validation of colorectal cancer and colonoscopy screening health beliefs scale for first-degree relatives of people with colorectal cancer (CCHBS-FDR) in China.Asia-Pacific journal of oncology nursing · 2025Article
- Influencing factors of colonoscopy screening in first-degree relatives of hospitalized colorectal cancer patients and preliminary clinical practices to improve the compliance.Frontiers in oncology · 2025Article
- Effectiveness of a tailored communication intervention on colonoscopy uptake for firstdegree relatives of colorectal cancer patients: A randomized controlled trial.Asia-Pacific journal of oncology nursing · 2022Article
- Applying the Health Belief Model to Quantify and Investigate Expectations for Computerized Cognitive Training.Journal of cognitive enhancement : towards the integration of theory and practice · 2021Article
- Diagnostic yield of colonoscopy surveillance in testicular cancer survivors treated with platinum-based chemotherapy: study protocol of a prospective cross-sectional cohort study.BMC gastroenterology · 2021Article
- A Systematic Review and Meta-Analysis on the Association between Inflammatory Bowel Disease Family History and Colorectal Cancer.Gastroenterology research and practice · 2021Review
- Cost-effectiveness analysis of alternative colorectal cancer screening strategies in high-risk individuals.Therapeutic advances in gastroenterology · 2021Article
- Hereditary colorectal cancer screening: A 10-year longitudinal cohort study following an educational intervention.Preventive medicine reports · 2020Article
- Colonoscopy Screening Behaviour and Associated Factors Amongst First-Degree Relatives of People with Colorectal Cancer in China: Testing the Health Belief Model Using a Cross-Sectional Design.International journal of environmental research and public health · 2020Article
- Familial Pancreatic Cancer and Surveillance of High-Risk Individuals.Gut and liver · 2019Review
- Family history of prostate and colorectal cancer and risk of colorectal cancer in the Women's health initiative.BMC cancer · 2017Article
- Familial pancreatic cancer: Concept, management and issues.World journal of gastroenterology · 2017Review
- Review
- Multiplex determination of serological signatures in the sera of colorectal cancer patients using hydrogel biochips.Cancer medicine · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted a systematic review and a meta-analysis of observational studies to identify and summarise the level of colorectal cancer (CRC) screening participation for people at increased risk due to family history of the disease. Medline, Cinhal, Embase and PsychInfo databases were comprehensively searched between January 1995 and May 2012 to identify relevant articles. To be included, studies had to report on screening for people who had at least one first-degree relative with CRC and no previous personal diagnosis of the disease. Pooled screening participation levels were calculated for each screening modality. Seventeen studies, accounting for a total of 13,269 subjects with a family history of CRC met the inclusion criteria. Seven studies, including a total of 6,901 subjects had a pooled faecal occult blood testing screening participation (at least once) of 25 % (95 % CI 12-38). Five studies including a total of 5,091 subjects had a pooled sigmoidoscopy-based screening participation (at least once) of 16 % (95 % CI 7-27). Seven studies including a total of 9,965 subjects had pooled participation colonoscopy-based screening (at least once) of 40 % (95 % CI 26-54). There was a significant level of screening heterogeneity between studies. This review identified a substantial underuse of CRC screening for people at increased risk of developing the disease. It highlights the potential opportunity that exists for increasing screening participation among this segment of the population and the need to adjust the current CRC screening policies towards that objective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.