Evidence map›Paper›PMID 23698781›Full record

ReviewInternational journal of molecular sciences2013

Nanoparticle-based systems for T(1)-weighted magnetic resonance imaging contrast agents.

Derong Zhu, Fuyao Liu, Lina Ma, Dianjun Liu, Zhenxin Wang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 94 citations in OpenAlex.

  1. Review
  2. Carbon Dots Meet MRI: Metal Doping for a Smart Contrast Agent Design.International journal of molecular sciences · 2026
    Review
  3. Synthesis of MnFeNanomaterials (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Review
  6. Exploring innovative strides in radiolabeled nanoparticle progress for multimodality cancer imaging and theranostic applications.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Manganese Ferrite Nanoparticles (MnFeNanomaterials (Basel, Switzerland) · 2020
    Article
  15. A Radio-Nano-Platform for T1/T2 Dual-Mode PET-MR Imaging.International journal of nanomedicine · 2020
    Article
  16. Article
  17. Article
  18. Review
  19. Multiwalled carbon nanotube hybrids as MRI contrast agents.Beilstein journal of nanotechnology · 2016
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Derong ZhuDepartment of Medicinal Chemistry and Pharmaceutical Analysis, Guangdong Medical College, Dongwan 523770, Guangdong, China. malina@ciac.jl.cn.
Fuyao Liu
Lina Ma
Dianjun Liu
Zhenxin Wang
Chinese Academy of Sciences · CNChangchun Institute of Applied Chemistry · CNGuangdong Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because magnetic resonance imaging (MRI) contrast agents play a vital role in diagnosing diseases, demand for new MRI contrast agents, with an enhanced sensitivity and advanced functionalities, is very high. During the past decade, various inorganic nanoparticles have been used as MRI contrast agents due to their unique properties, such as large surface area, easy surface functionalization, excellent contrasting effect, and other size-dependent properties. This review provides an overview of recent progress in the development of nanoparticle-based T1-weighted MRI contrast agents. The chemical synthesis of the nanoparticle-based contrast agents and their potential applications were discussed and summarized. In addition, the recent development in nanoparticle-based multimodal contrast agents including T1-weighted MRI/computed X-ray tomography (CT) and T1-weighted MRI/optical were also described, since nanoparticles may curtail the shortcomings of single mode contrast agents in diagnostic and clinical settings by synergistically incorporating functionality.

Indexed as

Contrast MediaGadolinium DTPAHumansMagnetic Resonance ImagingManganese CompoundsMultimodal ImagingNanoparticlesReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray ComputedContrast MediaGadolinium DTPAManganese Compounds

Identifiers

PMID23698781
PMCPMC3676856
OpenAlexW2149244406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.