ArticleInternational journal of molecular sciences2013
Characteristic of the pepper CaRGA2 gene in defense responses against Phytophthora capsici Leonian.
Article in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Chemical Priming by Neonicotinoids Unveils CaNEN4 as a Susceptibility Gene Against Phytophthora capsici in Pepper.Molecular plant pathology · 2026Article
- Genome-wide identification of RCC1 gene family in pepper (Capsicum annuum L.) and functional analysis of CaRCC1-16 under heat stress.Plant cell reports · 2026Article
- Molecular Interactions Between Soil-Borne Oomycetes and Plants: Infection Mechanisms, Host Resistance, and Implications for Sustainable Agriculture.Plants (Basel, Switzerland) · 2026Review
- CaSBP12 is implicated in pepper's defense resistance to Phytophthora capsici infection associated with the SA signaling pathway.BMC plant biology · 2025Article
- TheFrontiers in plant science · 2025Article
- Dual transcriptional characterization of spinach and Peronospora effusa during resistant and susceptible race-cultivar interactions.BMC genomics · 2024Article
- Pepper SBP-box transcription factor,Frontiers in plant science · 2024Article
- Transcriptome analysis ofFrontiers in microbiology · 2024Article
- Vegetable biology and breeding in the genomics era.Science China. Life sciences · 2023Review
- Transcriptomic analysis of bakanae disease resistant and susceptible rice genotypes in response to infection by Fusarium fujikuroi.Molecular biology reports · 2022Article
- The ectomycorrhizal fungusProceedings of the National Academy of Sciences of the United States of America · 2022Article
- The dissection of R genes and locus Pc5.1 in Phytophthora capsici infection provides a novel view of disease resistance in peppers.BMC genomics · 2021Article
- Article
- Overview of Biotic Stresses in Pepper (International journal of molecular sciences · 2020Review
- Transcription FactorInternational journal of molecular sciences · 2020Article
- Identification of PepperFrontiers in plant science · 2020Article
- Knockdown of the chitin-binding protein family gene CaChiIV1 increased sensitivity to Phytophthora capsici and drought stress in pepper plants.Molecular genetics and genomics : MGG · 2019Article
- A Novel Transcription FactorInternational journal of molecular sciences · 2018Article
- Genome-wide analysis of dirigent gene family in pepper (Capsicum annuum L.) and characterization of CaDIR7 in biotic and abiotic stresses.Scientific reports · 2018Article
- Challenges and Strategies for Breeding Resistance inFrontiers in plant science · 2018Review
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6 authors.
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Abstract
The most significant threat to pepper production worldwide is the Phytophthora blight, which is caused by the oomycete pathogen, Phytophthora capsici Leonian. In an effort to help control this disease, we isolated and characterized a P. capsici resistance gene, CaRGA2, from a high resistant pepper (C. annuum CM334) and analyzed its function by the method of real-time PCR and virus-induced gene silencing (VIGS). The CaRGA2 has a full-length cDNA of 3,018 bp with 2,874 bp open reading frame (ORF) and encodes a 957-aa protein. The protein has a predicted molecular weight of 108.6 kDa, and the isoelectric point is 8.106. Quantitative real-time PCR indicated that CaRGA2 expression was rapidly induced by P. capsici. The gene expression pattern was different between the resistant and susceptible cultivars. CaRGA2 was quickly expressed in the resistant cultivar, CM334, and reached to a peak at 24 h after inoculation with P. capsici, five-fold higher than that of susceptible cultivar. Our results suggest that CaRGA2 has a distinct pattern of expression and plays a critical role in P. capsici stress tolerance. When the CaRGA2 gene was silenced via VIGS, the resistance level was clearly suppressed, an observation that was supported by semi-quantitative RT-PCR and detached leave inoculation. VIGS analysis revealed their importance in the surveillance to P. capsici in pepper. Our results support the idea that the CaRGA2 gene may show their response in resistance against P. capsici. These analyses will aid in an effort towards breeding for broad and durable resistance in economically important pepper cultivars.
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