Melatonin-based therapeutics for neuroprotection in stroke.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed.

1. A multistage micro-nano biosystem prevents sepsis-associated encephalopathy through coordinated neuroinflammation suppression and gut-brain axis modulation.Bioactive materials · 2026
   Article
2. Melatonin as a Pleiotropic Modulator of Mitochondrial Function and Cellular Signaling in Ischemic Brain Injury.Cells · 2026
   Review
3. Multi-Target Neuroprotective Compound Exhibits EAAT2-Modulating and Alzheimer's Pathology-Attenuating Effects in In Vitro and In Vivo Models.ACS chemical neuroscience · 2026
   Article
4. Sleep Disorders and Stroke: Pathophysiological Links, Clinical Implications, and Management Strategies.Medical sciences (Basel, Switzerland) · 2025
   Review
5. Melatonin Promotes B-Cell Maturation and Attenuates Post-Ischemic Immunodeficiency in a Murine Model of Transient Focal Cerebral Ischemia.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
   Article
6. Significance of Melatonin in the Regulation of Circadian Rhythms and Disease Management.Molecular neurobiology · 2024
   Review
7. Circadian Factors in Stroke: A Clinician's Perspective.Cardiology and therapy · 2023
   Review
8. Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: From Bench to Bed-Side.International journal of molecular sciences · 2022
   Review
9. The Development of Novel Drug Treatments for Stroke Patients: A Review.International journal of molecular sciences · 2022
   Review
10. Ischemic Stroke and Sleep: The Linking Genetic Factors.Cardiology and therapy · 2021
    Review
11. Melatonin-A Potent Therapeutic for Stroke and Stroke-Related Dementia.Antioxidants (Basel, Switzerland) · 2020
    Review
12. Cerebrovascular Disease in the Young Adult: Examining Melatonin's Possible Multiple Roles.Journal of experimental neuroscience · 2019
    Review
13. Co-Administration of Progesterone and Melatonin Attenuates Ischemia-Induced Hippocampal Damage in Rats.Journal of molecular neuroscience : MN · 2018
    Article
14. The Incremental Induction of Neuroprotective Properties by Multiple Therapeutic Strategies for Primary and Secondary Neural Injury.International journal of molecular sciences · 2015
    Review
15. Neuroinflammatory responses to traumatic brain injury: etiology, clinical consequences, and therapeutic opportunities.Neuropsychiatric disease and treatment · 2015
    Review
16. Melatonin ameliorates brain injury induced by systemic lipopolysaccharide in neonatal rats.Neuroscience · 2014
    Article
17. Role of melatonin in traumatic brain injury and spinal cord injury.TheScientificWorldJournal · 2014
    Review
18. Neuroinflammation in traumatic brain injury: A chronic response to an acute injury.Brain circulation
    Review

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

Abstract

Indexed as