ArticleJournal of clinical microbiology2013
Real-time genomic epidemiological evaluation of human Campylobacter isolates by use of whole-genome multilocus sequence typing.
Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
82 citing papers in PubMed, 134 citations in OpenAlex.
- AcceleratingProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Strategies for integrating whole-genome sequencing into antimicrobial resistance surveillance.BMC genomics · 2026Review
- The Clonal Spread and Persistence ofPathogens (Basel, Switzerland) · 2025Article
- Evaluation of core genome and whole genome multilocus sequence typing schemes forMicrobial genomics · 2023Article
- Comparative genomics of Campylobacter jejuni from clinical campylobacteriosis stool specimens.Gut pathogens · 2022Article
- Genomic insights into zoonotic transmission and antimicrobial resistance in Campylobacter jejuni from farm to fork: a one health perspective.Gut pathogens · 2022Review
- Genomic Analysis Reveals That Isolation Temperature on Selective Media Introduces Genetic Variation inPathogens (Basel, Switzerland) · 2022Article
- Source Attribution of Human Campylobacteriosis Using Whole-Genome Sequencing Data and Network Analysis.Pathogens (Basel, Switzerland) · 2022Article
- Local accessory gene sharing among EgyptianMicrobial genomics · 2022Article
- Genomic Screening of Antimicrobial Resistance Markers in UK and USAntimicrobial agents and chemotherapy · 2022Article
- Whole Genome Multi-Locus Sequence Typing and Genomic Single Nucleotide Polymorphism Analysis for Epidemiological Typing ofFrontiers in microbiology · 2022Article
- Genomic adaptations of Campylobacter jejuni to long-term human colonization.Gut pathogens · 2021Article
- Impact of Ceftiofur Administration in Steers on the Prevalence and Antimicrobial Resistance ofMicroorganisms · 2021Article
- Reducing the Risk of Transmission of Critical Antimicrobial Resistance Determinants From Contaminated Pork Products to Humans in South-East Asia.Frontiers in microbiology · 2021Review
- Multi-Omics Approach Reveals the Potential Core Vaccine Targets for the Emerging Foodborne PathogenFrontiers in microbiology · 2021Article
- Select Phytochemicals ReduceFrontiers in microbiology · 2021Article
- Comparison of Molecular Subtyping and Antimicrobial Resistance Detection Methods Used in a Large Multistate Outbreak of Extensively Drug-Resistant Campylobacter jejuni Infections Linked to Pet Store Puppies.Journal of clinical microbiology · 2020Article
- Carvacrol attenuates Campylobacter jejuni colonization factors and proteome critical for persistence in the chicken gut.Poultry science · 2020Article
- Large waterborneEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020Article
- Microevolution of Campylobacter jejuni during long-term infection in an immunocompromised host.Scientific reports · 2020Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Sequence-based typing is essential for understanding the epidemiology of Campylobacter infections, a major worldwide cause of bacterial gastroenteritis. We demonstrate the practical and rapid exploitation of whole-genome sequencing to provide routine definitive characterization of Campylobacter jejuni and Campylobacter coli for clinical and public health purposes. Short-read data from 384 Campylobacter clinical isolates collected over 4 months in Oxford, United Kingdom, were assembled de novo. Contigs were deposited at the pubMLST.org/campylobacter website and automatically annotated for 1,667 loci. Typing and phylogenetic information was extracted and comparative analyses were performed for various subsets of loci, up to the level of the whole genome, using the Genome Comparator and Neighbor-net algorithms. The assembled sequences (for 379 isolates) were diverse and resembled collections from previous studies of human campylobacteriosis. Small subsets of very closely related isolates originated mainly from repeated sampling from the same patients and, in one case, likely laboratory contamination. Much of the within-patient variation occurred in phase-variable genes. Clinically and epidemiologically informative data can be extracted from whole-genome sequence data in real time with straightforward, publicly available tools. These analyses are highly scalable, are transparent, do not require closely related genome reference sequences, and provide improved resolution (i) among Campylobacter clonal complexes and (ii) between very closely related isolates. Additionally, these analyses rapidly differentiated unrelated isolates, allowing the detection of single-strain clusters. The approach is widely applicable to analyses of human bacterial pathogens in real time in clinical laboratories, with little specialist training required.
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