ArticleJournal of biomedical optics2013
Intravascular near-infrared fluorescence catheter with ultrasound guidance and blood attenuation correction.
Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- High-Speed Intravascular Near-Infrared Fluorescence-Ultrasound Imaging In Vivo.IEEE transactions on bio-medical engineering · 2026Article
- Intravascular ICG-enhanced NIRF-IVUS imaging to assess progressive atherosclerotic lesions in excised human coronary arteries.NPJ cardiovascular health · 2024Article
- Accounting for blood attenuation in intravascular near-infrared fluorescence-ultrasound imaging using a fluorophore-coated guidewire.Journal of biomedical optics · 2023Article
- Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging.Sensors (Basel, Switzerland) · 2021Review
- Quadruple ultrasound, photoacoustic, optical coherence, and fluorescence fusion imaging with a transparent ultrasound transducer.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Current Advances in the Diagnostic Imaging of Atherosclerosis: Insights into the Pathophysiology of Vulnerable Plaque.International journal of molecular sciences · 2020Review
- Intravascular Molecular Imaging: Near-Infrared Fluorescence as a New Frontier.Frontiers in cardiovascular medicine · 2020Review
- Hybrid intravascular imaging: recent advances, technical considerations, and current applications in the study of plaque pathophysiology.European heart journal · 2017Review
- Validating Intravascular Imaging with Serial Optical Coherence Tomography and Confocal Fluorescence Microscopy.International journal of molecular sciences · 2016Article
- Validating a bimodal intravascular ultrasound (IVUS) and near-infrared fluorescence (NIRF) catheter for atherosclerotic plaque detection in rabbits.Biomedical optics express · 2015Article
- Fluorescence lifetime imaging and intravascular ultrasound: co-registration study using ex vivo human coronaries.IEEE transactions on medical imaging · 2015Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Intravascular near-infrared fluorescence (NIRF) imaging offers a new approach for characterizing atherosclerotic plaque, but random catheter positioning within the vessel lumen results in variable light attenuation and can yield inaccurate measurements. We hypothesized that NIRF measurements could be corrected for variable light attenuation through blood by tracking the location of the NIRF catheter with intravascular ultrasound (IVUS). In this study, a combined NIRF-IVUS catheter was designed to acquire coregistered NIRF and IVUS data, an automated image processing algorithm was developed to measure catheter-to-vessel wall distances, and depth-dependent attenuation of the fluorescent signal was corrected by an analytical light propagation model. Performance of the catheter sensing distance correction method was evaluated in coronary artery phantoms and ex vivo arteries. The correction method produced NIRF estimates of fluorophore concentrations, in coronary artery phantoms, with an average root mean square error of 17.5%. In addition, the correction method resulted in a statistically significant improvement in correlation between spatially resolved NIRF measurements and known fluorophore spatial distributions in ex vivo arteries (from r = 0.24 to 0.69, p < 0.01, n = 6). This work demonstrates that catheter-to-vessel wall distances, measured from IVUS images, can be employed to compensate for inaccuracies caused by variable intravascular NIRF sensing distances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.