ArticleMedicine and science in sports and exercise2013
Effects of physical activity and muscle quality on bone development in girls.
Article in Medicine and science in sports and exercise, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Sedentary behaviour and bone health in children, adolescents and young adults: a systematic review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017Pooled it
- The National Osteoporosis Foundation's position statement on peak bone mass development and lifestyle factors: a systematic review and implementation recommendations.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Pooled it
- Trial
- Role of Body Fat and Metabolic Rate in Site-Specific Fracture Risk: A 20-Year Taiwanese Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Can physical activity counteract the negative effects of sedentary behavior on the physical and mental health of children and adolescents? A narrative review.Frontiers in public health · 2024Review
- Association Between the Growth Hormone/Insulin-Like Growth Factor-1 Axis and Muscle Density in Children and Adolescents of Short Stature.Frontiers in endocrinology · 2022Article
- Review
- Article
- Anterior Cruciate Ligament Research Retreat VIII Summary Statement: An Update on Injury Risk Identification and Prevention Across the Anterior Cruciate Ligament Injury Continuum, March 14-16, 2019, Greensboro, NC.Journal of athletic training · 2019Article
- Reference data for jumping mechanography in Canadian children, adolescents and young adults.Journal of musculoskeletal & neuronal interactions · 2016Article
- The effect of a 3-month moderate-intensity physical activity program on body composition in overweight and obese African American college females.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014Article
- Muscle density predicts changes in bone density and strength: a prospective study in girls.Journal of musculoskeletal & neuronal interactions · 2014Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
introductionPoor muscle quality and sedentary behavior are risk factors for metabolic dysfunction in children and adolescents. However, because longitudinal data are scarce, relatively little is known about how changes in muscle quality and physical activity influence bone development. PURPOSE: In a 2-yr longitudinal study, we examined the effects of physical activity and changes in muscle quality on bone parameters in young girls.
methodsThe sample included 248 healthy girls age 9-12 yr at baseline. Peripheral quantitative computed tomography was used to measure calf and thigh muscle density, an indicator of skeletal muscle fat content or muscle quality, as well as bone parameters at diaphyseal and metaphyseal sites of the femur and tibia. Physical activity was assessed using a validated questionnaire specific for youth.
resultsAfter controlling for covariates in multiple regression models, increased calf muscle density was independently associated with greater gains in cortical (β = 0.13, P < 0.01) and trabecular (β = 0.25, P < 0.001) volumetric bone mineral density and the bone strength index (β = 0.25, P < 0.001) of the tibia. Importantly, these relationships were generalized, as similar changes were present at the femur. Associations between physical activity and changes in bone parameters were weaker than those observed for muscle density. Nevertheless, physical activity was significantly (all P < 0.05) associated with greater gains in trabecular volumetric bone mineral density and the bone strength index of the distal femur.
conclusionsThese findings suggest that poor muscle quality may put girls at risk for suboptimal bone development. Physical activity is associated with more optimal gains in weight-bearing bone density and strength in girls, but to a lesser extent than changes in muscle quality.
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